Alcohol consumption has significant health, social and economic implications. Alcohol is the most prevalentpsychoactive substance used by Jamaican adolescents. The aim of this study was to determine whether alcohol isassociated with sexual risk behaviour among Jamaican adolescents. Methods: The data from National SecondarySchool Survey (NSS) conducted in 2013 was analysed. Descriptive statistics consisting of frequencies, percentagesand Pearson’s Chi square was done. Multivariate analysis was done using binary logistic regression. Result: The meanage of alcohol initiation among the participants was 12.3years [SD: 2.74]. There were significant associations betweengender (X2= 14.56; p= 0.000), relationship with father/guardian (X2: 10.71; P= 0.03), relationship with mother(X2= 15.16; P= 0.004) and conversation with parents/ guardians about dangers of drug abuse (X2= 8.16; P=0.004).Adolescents who were males (AOR= 0.62, 95% CI= 0.43 - 0.88), in the 8th grade (AOR= 0.51, 95% CI= 0.26 - 0.98) orin the 10th grade (AOR: 0.52, 95% CI: 0.32 - 0.85) were less likely to engage in sexual risk behaviour. Lifetime alcoholconsumption, past year alcohol consumption and past month alcohol consumption were not significantly associatedwith sexual risk behaviour (AOR= 0.35, 95% CI= 0.04 - 3.46; AOR= 1.75, 95% CI= 0.59 - 5.09, AOR= 0.78 95%CI= 0.56 - 1.11 respectively). Conclusion: Lifetime, past one year and past one month alcohol consumption amongthe students were not risk factors for sexual risk behavior (non-condom use) among Jamaican adolescents.