@article { author = {}, title = {The APOCP/APJCP - Taking Stock and Planning for the Future}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {79-80}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {}, keywords = {}, url = {https://journal.waocp.org/article_24166.html}, eprint = {https://journal.waocp.org/article_24166_ec0af6cb1e52c5aaedf50a2b1d53fed5.pdf} } @article { author = {}, title = {The 25th IACR Meeting - "Cancer Registration and Surveillance, Around the World"}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {81-82}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {}, keywords = {}, url = {https://journal.waocp.org/article_24167.html}, eprint = {https://journal.waocp.org/article_24167_ddb93a9c018e4857553b5b97c4034966.pdf} } @article { author = {}, title = {Targeting Angiogenesis – a Novel Mode in Cancer Chemoprevention}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {83-86}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {Cancer prevention is fast emerging as a discipline with a promising potential. Chemoprevention has its rationale ‍in the multistage process of carcinogenesis which provides an option for development of preventive approaches in ‍the early, premalignant stages, before appearance of clinical symptoms. Evidence is mounting that the angiogenic ‍switch may be an early event in carcinogenesis. Most chemopreventive agents currently under development probably ‍act via multiple mechanisms. The chemopreventives used in clinical trials, such as nonsteroidal anti-inflammatories, ‍tamoxifen and retinoids, have been shown to inhibit angiogenesis, the formation of new vessels from existing ‍vasculature, which may contribute to their protective effect. Development and use, alone or in combination with ‍other agents with other mechanisms of action, of specific antiangiogenic agents is likely to open new possibilities in ‍cancer chemoprevention. ‍}, keywords = {Angiogenesis,Cancer Prevention,eicosanoids,cyclooxygenases}, url = {https://journal.waocp.org/article_24168.html}, eprint = {https://journal.waocp.org/article_24168_7df2229926386a951df0815fd44ed144.pdf} } @article { author = {}, title = {Experimental Investigation of Opisthorchiasis-associatedCholangiocarcinoma Induction in the Syrian Hamster - Pointers for Control of the Human Disease}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {87-93}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {Appropriate animal models for specific diseases in man can facilitate elucidation of mechanisms underlying ‍tumour development and allow potential interventions and therapeutic regimens to be tested in vivo before ‍consideration for use in the human situation. In the North-east of Thailand exceptionally high levels of cholangiocellular ‍carcinomas (CCCs) are encountered, related to infestation with Opisthorchis viverrini liver flukes. The Syrian hamster ‍can also be infected with metacercariae of the fluke and heavy loads of parasites cause the development of cirrhotic ‍livers. While the presence of flukes alone does not give rise to neoplasms, large yields of cholangiofibrotic lesions and ‍CCCs can be readily induced with additional carcinogenic insult. While removal of the parasite with the antihelminthic ‍drug Praziquantel can protect against carcinogenesis, this is dependent on the timing of the drug administration and ‍the efficacy of application to the human situation remains to be confirmed. The available information would suggest ‍that interest needs to be concentrated on potential chemopreventive agents which could be administered to individuals ‍at high risk. Furthermore, understanding of the genesis of CCCs and the characteristics of preneoplastic lesions, ‍again as assessed in the animal model, might allow novel approaches to identification of early stage cases and effective ‍surgical intervention. ‍}, keywords = {Opisthorchiasis,hepatocarcinogens,hamster liver,cholangiocellular lesions,Chemoprevention}, url = {https://journal.waocp.org/article_24169.html}, eprint = {https://journal.waocp.org/article_24169_317e6b864d106d413189ad6d4a93c39d.pdf} } @article { author = {}, title = {Sarcoma in Iran}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {95-98}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {Purpose: To review the clinical characteristics of 1470 sarcoma cases and to define the factors in patients that ‍predict out come, relapse and survival . ‍Methods: Retrospective analysis of the database for the period 1991-2002, focusing on demographic, tumor related ‍and treatment related variables, relapse free survival (RFS) and overall survival (OS) using the Kaplan- Meier ‍method. Statistical significance was evaluated using the chi square and t- tests for univariate influence and a Cox ‍regression model for multivariate influence. ‍Results: Mean age was 30 years. The male to female ratio was 3/2 and 23%of the cases were under 16 years of ‍age. Median tumor diameter was 10.5 centimeters. The bone to soft tissue sarcoma ratio was 3/1 in children and 1/3 ‍in adults. Osteosarcoma, Ewing’s tumours and rhabdomyosarcomas accounted for 83% of childhood tumors. In ‍adults osteosarcomas, synovial sarcomas and malignant fibrous histocytomas (MFHs) were the most common subtypes. ‍Mean follow up time was 56 months. Of the total, 25% had initial metastasis, 86% received chemotherapy and 41 % ‍underwent radiotherapy. The main prognostic factors for survival were tumor size, margin of surgery, neurovascular ‍involvement in the pathological report, initial metastasis and no complete response to first therapy. Adjuvant ‍radiotherapy, small tumor size, curative surgery with chemotherapy and free surgical margins were significantly ‍associated with reduced recurrence. ‍Conclusion: Our patients are characterised by diagnosis with a large tumor size, advanced stage of disease and ‍short survival. A complete response to primary therapy is the main independent variable for overall survival. Earlier ‍diagnosis and an experienced team including surgical, medical and radiotherapy oncologists are needed for a better ‍response and longer survival of patients. ‍}, keywords = {Sarcoma,clinicopathological parameters,survival,Iran}, url = {https://journal.waocp.org/article_24170.html}, eprint = {https://journal.waocp.org/article_24170_94271d6c50b1d8a19d2670f8fc00dec9.pdf} } @article { author = {}, title = {A Comparison of Cytology with Pap Smears Taken by a Gynecologist and with a Self-sampling Device}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {99-102}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {Cervical cancer is the most common cancer in Thai women and as yet screening programmes are minimally ‍effective. The Pap smear is the test accepted to be most appropriate for cervical cancer screening so far. One of the ‍main reasons why women do not come to have Pap smear done is “shyness”, which weakens compliance with ‍recommendations to undergo Pap smear with pelvic examination. The self-administered device by the Kato method ‍was established to overcome this problem and the present study was carried out to confirm the adequacy of the ‍specimens obtained with this technique in comparison with specimens collected by gynecologists. Two hundred ‍women were invited to participate in the study voluntarily. Each was allocated to have a Pap smear conducted by a ‍gynecologist and then instructed to produce a self-obtained smear using Kato’s device. The cytology results of Pap ‍smears from both methods were compared to test for agreement using Kappa statistics. ‍There was agreement between the adequacy of smears collected by gynecologists and those self-sampled with the ‍percentage agreement of 96.5% and a Kappa score of 0.43 (95% CI 0.33-0.54, P<0.001). There were 8 cases detected ‍as epithelial cell abnormalities from the cervical cells collected by gynecologists and also with the self-administered ‍technique. Good agreement for detection of cellular changes was found with a percentage of 78.0% and the Kappa’s ‍score was 0.61 (95% CI 0.46-0.76, P<0.001). The results from this study provide convincing evidence that the selfadministered ‍device can be an alternative choice for women who are too shy to undergo pelvic examination or even ‍for those who have limited time to visit health care centers or doctors to have a Pap smear test.}, keywords = {Self-administered device,cervical cells,Pap smear}, url = {https://journal.waocp.org/article_24171.html}, eprint = {https://journal.waocp.org/article_24171_00b5e9436de013b7beea810d93649745.pdf} } @article { author = {}, title = {The Coverage of Cervical Cancer Screening in Khon Kaen, Northeast}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {103-105}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {Cervical cancer is a common cancer in Thai women and one of the only cancers that can be readily cured if early ‍detection is successful. The Pap smear is an accepted as an appropriate means for cervical cancer screening at ‍present. However, there are still some management problems with early detection programmes. Since data showing ‍how many women have been screened by Pap smear are limited in Thailand, the present study was conducted with ‍the aim of determining coverage in a defined population in the sample area, Thakaserm sub- district in Nampong ‍district, Khon Kaen province, Thailand. The investigation was carried out during June-August 2000 to collect ‍information on history of screening for cervical cancer using questionnaires. All women aged 20 and above were ‍asked to answer the set of questionnaires a total of 1,199 women responded. There were 66.9% that reported having ‍received a Pap smear test for screening for cervical cancer at least once. However, there were 33.1 % that had never ‍undergone a Pap smear in their life. It is important to find a strategy to increase the coverage of cervical cancer ‍screening programme for this population. ‍}, keywords = {Cervical cancer screening - Khon Kaen,Thailand - early detection programmes}, url = {https://journal.waocp.org/article_24172.html}, eprint = {https://journal.waocp.org/article_24172_d5ce85f6bead1ce322fc1171f4ae50c2.pdf} } @article { author = {}, title = {Different Risk Relations with Smoking for Non-small-cell lung Cancer: Comparison of TP53 and TP73 Genotypes}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {107-112}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {Background: The association between TP53/TP73 gene polymorphisms and tobacco smoking was evaluated with ‍regard to risk of non-small cell lung cancer (NSCLC). Methods: A case-control study with 192 histologically confirmed ‍NSCLC cases and 241 non-cancer controls was conducted. Subjects were genotyped for TP53 Arg72Pro and TP73 ‍G4C14 to A4T14 polymorphisms by PCR-based methods. Risk and interactions were assessed as odds ratios (ORs) ‍and 95% confidence intervals (CIs). Results: The analyses according to TP53 genotypes for the risk of tobacco ‍smoking illustrated that risk with heavy smoking was much higher for subjects with the TP53 ProPro genotype ‍(OR: 16.4, 95% CI 1.77-151.7) as compared with those with TP53 ArgArg/ArgPro (3.36, 1.69-6.68). Similar analyses ‍for TP73 genotypes did not show any differences for NSCLC risk. Conclusion: A risk relation of heavy smoking for ‍the NSCLC is suggested with the TP53 but not the TP73 polymorphism. ‍}, keywords = {non-small-cell lung cancer,p53,P73,Polymorphism,smoking,gene-environment interaction}, url = {https://journal.waocp.org/article_24173.html}, eprint = {https://journal.waocp.org/article_24173_dd1a0ae609fc46c9a793e0f859c99ab3.pdf} } @article { author = {}, title = {Significance of Plasma IgA and IgG Antibodies to Epstein-Barr Virus Early and Viral Capsid Antigens in Thai Nasopharyngeal Carcinoma}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {113-118}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {Epstein-Barr virus (EBV) is an important causal factor of human nasopharyngeal carcinoma (NPC). High levels ‍of serum IgA and IgG antibodies to EBV early and viral capsid antigens (IgA/EA, IgA/VCA, IgG/EA and IgG/VCA) ‍have been reported in NPC patients. Since specific serum IgA/EA, IgA/VCA and IgG/EA are claimed to be useful ‍serological markers for NPC. In order to evaluate whether plasma IgA/EA, IgA/VCA, IgG/EA and IgG/VCA antibody ‍levels are useful markers for diagnosis and prognosis of Thai NPC, we examined the prevalence of these antibodies ‍in 79 NPC patients, and 127 age-matched controls (47 healthy subjects (HS), 32 cases of other disease (OD) and 48 ‍cases of other cancer (OC)) by using an indirect immunofluorescence assay. The prevalence of plasma IgA/EA, IgA/ ‍VCA, and IgG/EA in NPC patients (55.7, 68.4 and 68.4%) was significantly higher than in the HS (0.0, 0.0 and ‍20.5%,), OD (0.0, 0.0 and 3.1%) and OC (0.0, 0.0 and 20.8%) groups (p<0.05). The prevalence of plasma IgG/VCA ‍in NPC patients (93.7%) was significantly different from those for the OD and OC groups (71.9 and 43.8%) but not ‍for the HS group (89.4%). In NPC patients, the geometric mean titers (GMT) of plasma IgA/EA, IgA/VCA and IgG/ ‍EA were increased with an advanced clinical stage of disease but not IgG/VCA. In contrast, GMT of IgG/VCA was ‍increased with aggressive type of disease (histological type) but not IgA/EA, IgA/VCA, and IgG/VCA. The results of ‍our study suggest that plasma IgA/EA, IgA/VCA and IgG/EA antibodies may be useful markers for diagnosis and ‍assessing prognosis of Thai NPC. ‍}, keywords = {Nasopharyngeal carcinoma,Epstein-Barr Virus,Plasma,Antibody,Thailand}, url = {https://journal.waocp.org/article_24174.html}, eprint = {https://journal.waocp.org/article_24174_e7592f4a44e32666c7e035d388daf533.pdf} } @article { author = {}, title = {Risk Factors for Oesophageal Cancer in Linzhou, China: a Case-Control Study}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {119-124}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {Linzhou City has one of the highest incidences of oesophageal cancer in China, and in the world. A case-control ‍study was here conducted to investigate potential risk factors in this area. Linzhou Cancer Registry was used to ‍identify cases of oesophageal cancer, aged between 30 and 75, diagnosed between January 1998 and April 1999. ‍Three neighbourhood controls were selected for each case, matched according to age, sex and village of residence. A ‍total of 211 cases and 633 controls were interviewed. A strong association was found between socio-economic status ‍and the risk of oesophageal cancer. Increased income, residential space and education were all significantly associated ‍with a decreased risk (OR 0.54, 0.36 and 0.30 respectively). Using a drinking water source other than tap water was ‍significantly associated with an increased risk (OR 5.49). The consumption of beans, vegetables and vinegar all ‍showed a protective effect with odds ratios of 0.37, 0.44 and 0.37 respectively. Preferences for a low salt diet or a high ‍salt diet were both associated with an increased risk. It can be concluded that in Linzhou, oesophageal cancer is a ‍disease related to poverty. Having a drinking water source other than tap water increases the risk of oesophageal ‍cancer. As in other populations, a high consumption of vegetables and beans are associated with a decreased risk and ‍a preference for a high salt diet is associated with an increased risk. ‍}, keywords = {Oesophageal cancer - risk factors - Linzhou,China - case-control}, url = {https://journal.waocp.org/article_24175.html}, eprint = {https://journal.waocp.org/article_24175_337ea3ad047410296c7f4d4a9624b492.pdf} } @article { author = {}, title = {Cancer of the Oral Cavity and Pharynx in Karachi - Identification of Potential Risk Factors}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {125-130}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {The objective of the study was to provide an overview of the demographics of cancer of the oral cavity and ‍pharynx in Karachi South (1995-2001), and identify potential risk factors. Cases recorded for Karachi South, at ‍Karachi Cancer Registry during 1st January 1995 to 31st December 2002 were analysed. For maximum completion ‍of data cancer cases, recorded from 1st January 1995 to 31st December 2001 were included for final analysis. The age ‍standardized incidence rates per 100,000 population (ASIRs) for cancer of the oral cavity (excluding salivary gland) ‍in Karachi South were 17.1 and 16.5 in males and females whereas the ASIRs for cancer of the pharynx (excluding ‍nasopharynx) were 7.1 and 2.4 in males and females, respectively. The oral pharyngeal ratios were 2.4 and 6.9 for ‍males and females and gender ratios (M F) were 1.04 for the oral cavity and 3.0 for the pharynx. The mean ages were ‍51 years (95% CI 49.6; 52.2) and 56.1 years (95% CI 54.4; 57.8) respectively. Cancer of the oral cavity ranked 2nd in ‍Karachi in both genders. Cancer of the pharynx ranked 7th in males and 14th in females. Approximately 97% of the ‍oral cavity and pharyngeal cancers were histologically confirmed. The majority of the oral (47.1%) and pharyngeal ‍(51.9%) cancer cases presented as grade II lesions, and were discovered at advanced stages. Of the cancers reported ‍during 1995-2001, 60.4% of the oral and 78.1% of the pharyngeal lesions had spread to a distant site at the time of ‍diagnosis. Squamous cell carcinoma comprised 96.5% and 91.8% of the totals. The incidences of these cancers are ‍comparable to the highest risk regions of the world. As distinct from other geographical areas oral cancer is as ‍common in females as in males, which may reflect the pattern of exposure to known risk factors such as betal quid, ‍arecanut and tobacco and the absence of alcohol as a risk factor in both genders. Apergillus contamination of ‍arecanut could also be a risk factor but no confirmation studies or quantification is available. Despite the common ‍risk factors, incidence of pharyngeal cancer is three times higher in men as compared with women. The keys to ‍reducing the incidence and mortality due to oral and pharyngeal cancers are prevention and control, emphasizing ‍cessation of tobacco use and cancer screening. However a targeted cancer and tobacco control program does not ‍presently exist in Pakistan. ‍}, keywords = {cancer,oral cavity,pharynx,Karachi,Pakistan}, url = {https://journal.waocp.org/article_24176.html}, eprint = {https://journal.waocp.org/article_24176_839cb5e8389164f46163a1ea8a86f350.pdf} } @article { author = {}, title = {Chemomodulatory Effect of Moringa Oleifera, Lam, on Hepatic Carcinogen Metabolising Enzymes, Antioxidant Parameters and Skin Papillomagenesis in Mice}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {131-139}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {The modulatory effects of a hydro-alchoholic extract of drumsticks of Moringa oliefera Lam at doses of 125 mg/ ‍kg bodyweight and 250 mg/ kg body weight for 7 and 14 days, respectively, were investigated with reference to drug ‍metabolising Phase I (Cytochrome b5 and Cytochrome P450 ) and Phase II (Glutathione-S- transferase) enzymes, ‍anti-oxidant enzymes, glutathione content and lipid peroxidation in the liver of 6-8 week old female Swiss albino ‍mice. Further, the chemopreventive efficacy of the extract was evaluated in a two stage model of 7,12 – ‍dimethylbenz(a)anthracene induced skin papillomagenesis. Significant increase (p<0.05 to p<0.01) in the activities ‍of hepatic cytochrome b5, cytochrome P450, catalase, glutathione peroxidase ( GPx ), glutathione reductase (GR), acid ‍soluble sulfhydryl content (-SH ) and a significant decrease ( p<0.01 ) in the hepatic MDA level were observed at ‍both dose levels of treatment when compared with the control values. Glutathione-S- transferase ( GST )activity was ‍found to be significantly incr eased (p<0.01 ) only at the higher dose level. Butylated hydr oxyanisol (BHA ) fed at a ‍dose of 0.75% in the diet for 7 and 14 days (positive control ) caused a significant increase (p<0.05 to p<0.01) in the ‍levels of hepatic phase I and phase II enzymes, anti- oxidant enzymes, glutathione content and a decrease in lipid ‍peroxidation. The skin papillomagenesis studies demonstrated a significant decrease (p<0.05 ) in the percentage of ‍mice with papillomas, average number of papillomas per mouse and papillomas per papilloma bearing mouse when ‍the animals received a topical application of the extract at a dose of 5mg/ kg body weight in the peri-initiation phase ‍7 days before and 7 days after DMBA application, Group II ), promotional phase (from the day of croton oil application ‍and continued till the end of the experiment, Group III ) and both peri and post initiation stages (from 7 days prior ‍to DMBA application and continued till the end of the experiment, Group IV) compared to the control group (Group ‍I ). The percentage inhibition of tumor multiplicity has been recorded to be 27, 72, and 81 in Groups II, III, and IV, ‍respectively. These findings are suggestive of a possible chemopreventive potential of Moringa oliefera drumstick ‍extract against chemical carcinogenesis.}, keywords = {Chemoprevention,hepatic biotransformation enzymes,anti-oxidant defense,DMBA,skin papillomagenesis,Moringa oliefera Lam}, url = {https://journal.waocp.org/article_24042.html}, eprint = {https://journal.waocp.org/article_24042_5b4473e36ef04cb16961419757bf1368.pdf} } @article { author = {}, title = {Multiphasic Epidemiological Analyses on Smoking Habits among Undergraduate Students in Japan}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {141-145}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {Little is known about the prevalence and dynamics of smoking habits among university students in Japan, and ‍their association with other lifestyle parameters and biological markers. Data on undergraduate students were here ‍extracted from the questionnaire and laboratory tests of the periodic health checkup of Kyoto University in 2000 ‍and 2001. In addition to simple statistics, longitudinal analyses were performed using logistic regression, and the ‍odds ratio (OR) and its 95% confidence interval (CI) were calculated for each item. Among 11,203 subjects, 12.1% ‍had a smoking habit. The smoking rate was higher in men than in women (14.4% vs 2.4%, P<0.001) and increased ‍from 2.5% (freshmen) to 18.3% (seniors) with advance in year. During one year of follow-up, 5.8% of students newly ‍acquired a smoking habit, and 12.4% of smokers abandoned the habit. Compared with students majoring in natural ‍sciences, the majors in humanities or social sciences were more likely to begin smoking (OR=1.32, 95% CI=1.06- ‍1.65). Taking up smoking was more common among those who consumed alcohol (OR=1.98, 95% Cl=1.56-2.51), and ‍skipped breakfast and dined out more frequently (trend P<0.001 for both), but less common among regular exercisers ‍(OR=0.71, 95% Cl=0.56-0.90). Smoking habits tended to be associated with subsequent proteinuria (adjusted OR=1.39, ‍95% Cl=0.96-2.00) and subsequent cough or phlegm (adjusted OR=1.56, 95% Cl=0.91-2.67). This study revealed ‍that the proportion of student smokers increases with the year in university, in association with several other lifestyle ‍parameters. Measures should be taken against smoking behavior focusing on freshmen and considering their lifestyle.}, keywords = {undergraduate students,smoking,Lifestyle,health checkup,logistic regression}, url = {https://journal.waocp.org/article_24043.html}, eprint = {https://journal.waocp.org/article_24043_5acd948fc5cc8a18004033564d530301.pdf} } @article { author = {}, title = {Serum Antioxidant Vitamin Levels of People in Khon Kaen, Northeastern Thailand}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {147-152}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {Three antioxidant vitamins, the á- and â-carotenes as well as vitamin E, were measured in sera of a normal ‍population in Northeastern Thailand using HPLC. The mean serum â-carotene level of females was significantly ‍higher than the value for males, i.e, 37.55 (95%CI=34.59-40.51) versus 32.97 (95%CI=30.01-35.93) ìg/dl. The â- ‍carotene level tended to decrease as age increased, particularly in the male population. The mean serum á-carotene ‍level was also higher in females than in males, i.e., 7.08 (95%CI=6.57-7.59) and 6.26 (95%CI=5.77-6.75) ìg/dl, ‍respectively. The average serum á-tocopherol (Vitamin E) level of the whole population was 1.08 (95%CI=1.04-1.12) ‍ìg/dl and did not show age or sex differences. In general, the serum antioxidant vitamins of smokers were lower than ‍those of the non-smokers but a significant difference was observed only for á-tocopherol. Alcohol drinking resulted ‍in slightly lower serum â-carotene values, whereas coffee or tea drinking and betel nut chewing did not cause any ‍differences with these three antioxidant vitamins. However, we report higher in serum á-carotene levels of people in ‍Ban Fang district than in Chonnabot district. The results from our study give the base line data of serum antioxidant ‍vitamins in a Thai population and also suggest future intensive study on the relationship of dietary intake and ‍cancer prevention. ‍}, keywords = {Carotenes,α-Tocopherol,antioxidants,Serum,Thailand,HPLC}, url = {https://journal.waocp.org/article_24177.html}, eprint = {https://journal.waocp.org/article_24177_f2290e32dcc6e40c82f37569b19fdca5.pdf} } @article { author = {}, title = {Grand Challenges in Global Health and the Practical Prevention Program? Asian Focus on Cancer Prevention in Females of the Developing World}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {153-165}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {In response to the request for ‘Breakthrough Questions’ for ‘Grand Challenges in Global Health’ recently ‍published in Nature, the Asian Pacific Organization for Cancer Prevention should focus its attention on what projects ‍are of the highest priority for integration with its Practical Prevention Program (PPP). The most common female ‍cancers in most of the countries of Asia are carcinoma of the breast, followed by the uterine cervix. While the ‍incidences of breast adenocarcinomas are still generally lower than in the Western world they are rapidly increasing, ‍and squamous cell carcinomas of the cervix are a major problem. Clearly there are many areas which would reward ‍research. One factor which appears of major relevance in the mammary gland case is the diet, and particularly the ‍phytoestrogens included in ‘tofu’, along with physical exercise. The age at which these could be operating needs to ‍be elucidated, with reference to timing of menarche and menopause, and also breast mammographic density, another ‍predictor of likelihood of neoplasia. In the cervix, the predominant influence is well established to be persistent ‍infection with a high risk ‘oncogenic’ type of human papilloma virus (HPV). Vaccines therefore hold much promise, ‍but a better understanding of the mechanisms underlying spontaneous clearance of both infection and cervical ‍intraepithelial neoplasia (CIN) of different grades is also essential for optimal intervention. The roles of smoking ‍and antioxidant intake in particular deserve emphasis. In Asia, with the considerable variation evident in both ‍breast and cervical cancer incidence rates, as well as in cultural and other environmental factors, we are in a very ‍favourable position to meet two specific challenges: 1) elucidation of how diet in adolescence determines susceptibility ‍to neoplasia of the mammary glands; and 2) determination of what governs persistence of HPV infection. Realisation ‍of these pivotal research aims, with especial emphasis on the context of the PPP, is our shared goal.}, keywords = {Major female cancers,research challenges,Prevention,Lifestyle,diet in adolescence,HPV infection}, url = {https://journal.waocp.org/article_24178.html}, eprint = {https://journal.waocp.org/article_24178_3acbb54db123952976d664618babe1ad.pdf} } @article { author = {}, title = {World Cancer Report}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {166-167}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {}, keywords = {}, url = {https://journal.waocp.org/article_24179.html}, eprint = {} } @article { author = {}, title = {17th Asia Pacific Cancer Congress, 8-11th October, Bali, Indonesia‘Improving Basic Oncology and Its Clinical Application for Better Cancer Control in the Asia Pacific Region’}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {167-168}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {}, keywords = {}, url = {https://journal.waocp.org/article_24180.html}, eprint = {} } @article { author = {}, title = {First Regional APOCP Conference - Western AsiaEge University, 14-16th October, Izmir, Turkey‘New Strategies for Cancer Control’}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {168-169}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {}, keywords = {}, url = {https://journal.waocp.org/article_24181.html}, eprint = {} } @article { author = {}, title = {Asian Pacific Organization for Cancer Prevention (APOCP) ASIATOX III Satellite Symposium - 28-29th November, Bangkok‘In Vivo Models for Assessment of Carcinogenicity and Chemopreventive Potential of Food Components’}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {169-170}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {}, keywords = {}, url = {https://journal.waocp.org/article_24182.html}, eprint = {} } @article { author = {}, title = {ASIATOX III, 30th November- 5th December,Bangkok- Chiang Mai, Thailand‘International Toxicology Harmonization : The Challenge of Asia’}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {170-171}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {}, keywords = {}, url = {https://journal.waocp.org/article_24183.html}, eprint = {} } @article { author = {}, title = {Second Regional APOCP Conference - South East AsiaKhon Kaen University, 26-28th January, 2004, Thailand‘Customs, Environment and Cancer’}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {4}, number = {2}, pages = {171-172}, year = {2003}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {}, keywords = {}, url = {https://journal.waocp.org/article_24184.html}, eprint = {} }