@article { author = {}, title = {Lobaplatin Combined Floxuridine/Pirarubicin-based Transcatheter Hepatic Arterial Chemoembolization for Unresectable Primary Hepatocellular Carcinoma}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {15}, number = {5}, pages = {2057-2060}, year = {2014}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {}, abstract = {Purpose: To assess the effect and safety of lobaplatin combinated floxuridine /pirarubicin in transcatheterhepatic arterial chemoembolization(TACE) of unresectable primary liver cancer. Patients and Methods: TACEcombined with the chemotherapy regimen was used to treat 34 unresectable primary liver cancer patients. DSA/MRI/CT/blood routine examinations were used to evaluate short term activity and toxicity after 4-5 weeks,the process being repeated if necessary. Results: Among the 34 cases, 1 (2.9%) showed a complete response, 21(61.7%) a partial response, 8 (23.5%) stable disease, and 4 progressive disease, with a total effective rate of 67.6%.The content of alpha fetoprotein dropped by over 50% in 20 cases (58.8%). The rate of recovery was hepatalgia(88.2%), ascites (47.1%), appetite (55.9%), Performance Status(30.4%). The median follow-up time (MFT) was281 days (63-558 days), and median progression-free survival was 118.5 days (95%, CI:88.8-148.2days). Adversereactions (III-IV grade) were not common, with only 4 cases of vomiting and 2 cases of thrombocytopenia (IIIgrade). Conclusions: Lobaplatin-based TACE is an effective and safe treatment for primary liver cancer.}, keywords = {primary hepatic carcinoma,Chemoembolization,platinum chemotherapy,clinical response}, url = {https://journal.waocp.org/article_28876.html}, eprint = {https://journal.waocp.org/article_28876_55d9b33a4354605d5ecb979e95023e66.pdf} }