@article { author = {Machida, Yuichiro and Sagawa, Motoyasu and Tanaka, Makoto and Motono, Nozomu and Matsui, Takuma and Usuda, Katsuo and Uramoto, Hidetaka}, title = {Postoperative survival According to the Glasgow Prognostic Score in Patients with Resected Lung Adenocarcinoma}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {17}, number = {10}, pages = {4677-4680}, year = {2016}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {10.22034/APJCP.2016.17.10.4677}, abstract = {  Background: The Glasgow Prognostic Score (GPS) is calculated from measured CRP and albumin levels. We here evaluated the significance of the GPS in patients with resected pulmonary adenocarcinoma. Materials and Methods: The present study included 156 patients with lung adenocarcinoma who underwent lobectomy at Kanazawa Medical University between 2002 and 2012. Classification was into three groups: those with normal albumin (>=3.5 g/dl) and C-reactive protein (CRP) (<=1.0 mg/dl) levels were classified as GPS 0 (n =136), those with low albumin (1.0 mg/dl) levels as GPS 1 (n = 16), and those with low albumin (1.0 mg/dl) levels as GPS 2 (n = 4). We retrospectively investigated relationships between the patient characteristics including the GPS, and disease-free survival and cancer-specific survival. Results: The pathological stages of the patients were as follows: IA (n=78, 50%), IB (n=31, 19.9%), IIA (n=20.0, 12.8%), IIB (n=9.0, 5.7%), and IIIA (n=18.0, 11.5%). Lobectomy was performed in all cases. The average GPS was 0.15 (0-2) and showed significant relationships with stage and tumor size. The 2-year survival rates in patients with GPS0, 1 and 2 were 81.4%, 38.4%, and 25.0%, respectively. Clear correlations were noted with both cancer-specific survival and disease-free survival. Furthermore, multivariate analysis revealed that GPS was a significant prognostic factor. Conclusions: The GPS could be a prognostic factor for patients with resected pulmonary adenocarcinoma.}, keywords = {}, url = {https://journal.waocp.org/article_40508.html}, eprint = {https://journal.waocp.org/article_40508_bd3da5a5fd6f60d53eddc4f9d4b0292b.pdf} }