@article { author = {Mukhtar, Shazia and Khan, Sohail and Hussain, Munawar and Adil, Syed}, title = {Role of Multidetector Computed Tomography in Evaluation of Ovarian Lesions in Women Clinically Suspected of Malignancy}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {18}, number = {8}, pages = {2059-2062}, year = {2017}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {10.22034/APJCP.2017.18.8.2059}, abstract = {  Objective: To determine the diagnostic accuracy of multidetector computed tomography (MDCT) in the evaluation of ovarian carcinoma using histopathology as the gold standard. Methods: This prospective cross-sectional study was conducted at Department of Radiology, Dow international medical college, DUHS, Karachi from December 2015 to April 2016. All patients of 30-60 years of age who were referred for CT a scan of the abdomen and pelvis with clinical suspicion of malignant ovarian cancer were included. A total of 158 cases were assessed with signs and symptoms of weight loss and an abdominal or pelvic mass detected on examination by a physician. Results: The mean age was 42.7 ±10.3 years (range 30-60). The largest group (46, 29.1%) presented with Stage 0 disease. The mean duration of symptoms was 4.06 ±1.39 months (range 1-6). Taking histopathology as the gold standard the sensitivity, specificity, NPV, PPV and overall diagnostic accuracy values for MDCT were 95.6%, 97.3%, 93.5%, 97.3% and 96.8%, respectively. Conclusion: MDCT showed high accuracy in differentiating benign and malignant lesions and as well as staging of malignant cases which should be very helpful in management of ovarian disease.}, keywords = {Multidetector computed tomography,ovarian carcinoma,histopathology}, url = {https://journal.waocp.org/article_49597.html}, eprint = {https://journal.waocp.org/article_49597_20d098979fb2ae9e98fd2f68945c9342.pdf} }