@article { author = {Farhadi, Sareh and Jolehar, Maryam and Safapour, Fatemeh}, title = {Micronucleus Assay of Buccal Mucosal Cells in Hairdressers: The Importance of Occupational Exposure}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {19}, number = {8}, pages = {2131-2134}, year = {2018}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {10.22034/APJCP.2018.19.8.2131}, abstract = {Background and objective: Today, the chemical materials available in hair dyes are considered risk factors for manycancers, particularly oral cancer. This study was performed to study the effect of occupational exposure on micronucleus(MN) frequency of buccal mucosa cells in hairdressers. Materials and methods: This historical cohort study wasperformed on 28 hairdressers and 28 control samples. To eliminate the gender variable, all the samples were womenand they were matched by age. Buccal mucosa cells were removed using a wet spatula and after fixation, Papanicolaoustaining method was applied. The percentage of the cells containing MN was registered. T-test was used to comparethe results between the two groups. Results: The mean percentages of MN in buccal mucosa cells of hairdresser’s andcontrol sample were 16.61±4.95 and 8.84±4.74, respectively, with a significant difference (P<0.001). In addition, higherMN mean percentage was reported in subjects working more than 60 hours weekly compared with those working 60hours and less; however, the difference was not statistically significant (P=0.14). Conclusion: In the present study,hairdressers demonstrate significantly higher average of MN in buccal mucosa cells. Also, it seems increment in theirworking time can increase MN frequency in these studied samples.}, keywords = {micronucleus,nuclear change,hairdresser,buccal mucosa}, url = {https://journal.waocp.org/article_66084.html}, eprint = {https://journal.waocp.org/article_66084_2f1a3cfe3c67cdcf7c54efc6aa981236.pdf} }