@article { author = {Malekpour Afshar, Reza and Balar, Negin and Mollaei, Hamid Reza and Arabzadeh, Seyed Alimohammad and Iranpour, Maryam}, title = {Low Prevalence of Human Papilloma Virus in Patients with Breast Cancer, Kerman; Iran}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {19}, number = {11}, pages = {3039-3044}, year = {2018}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {10.31557/APJCP.2018.19.11.3039}, abstract = {Breast cancer is the first of the most important causes of the deaths of women in the world and in Iran. There arevarious causes and causes of this cancer, one of which has recently been described as a cause of breast cancer, is the humanpapillomavirus (HPV). The HPV is transmitted through sexual contact and skin lesions. There are more than 100 types ofHPV that can influence different parts of the body. Some types of HPV can cause cancer (such as cervical or anal cancer)and others can cause warts (such as genital or plantar warts). To study the risk of HPV infection in Breast Cancer, wemanaged a Case-Control study in Kerman, southeast of Iran. For this purpose, 98 paraffin blocks of breast cancer and40 paraffin blocks of fibrocystic as a control were tested for the presence of HPV DNA using Real-Time PCR, andHPV typing was done using INNo-Lippa assay. HPV DNA was detected in 8 out of 98 patients (8.2%), while it wasnot detected in the control group samples. HPV types 16, 18 were the most common (62.5%) types in positive samples.The prevalence of HPV in patients with breast cancer of Iran is very low and less than other regions of the world,it seems that maybe rout of transmission of HPV in Iran is under control. No one knows exactly why breast canceroccurs. The environment, hormones, Viruses, or your lifestyle could all play a role in the development of breast cancer.Currently, Vaccination is the best way to prevent cancer that’s due to HPV. However, additional studies on the largergroup of patients are needed to explain the roles of HPV in Breast cancer.}, keywords = {breast cancer,Human papilloma virus,Kerman,Iran}, url = {https://journal.waocp.org/article_70496.html}, eprint = {} }