@article { author = {Arora, Karandeep Singh and Bansal, Rahul and Mohapatra, Shreeyam and Verma, Akshay and Sharma, Sakshi and Pareek, Shubhangi}, title = {Prevention of Malignant Transformation of Oral Leukoplakia and Oral Lichen Planus Using Laser: An Observational Study}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {19}, number = {12}, pages = {3635-3641}, year = {2018}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {10.31557/APJCP.2018.19.12.3635}, abstract = {Objectives: The present observational study was conducted with an aim to evaluate the efficacy of diode laser inmanagement of homogenous oral leukoplakia (OL) and reticular oral lichen planus (OLP), so that these potentiallymalignant disorders can be limited and further malignant transformation can be prevented. Further the assessmentof associated postoperative complications after laser therapy was also carried out. Study Design: Present study wascarried out using diode laser 810nm on 60 subjects, of whom 30 subjects were of homogenous OL and 30 subjectswere of reticular OLP aged between 20 – 60 years, the diagnosis of which was histopathologically confirmed. Results:Of the 60 subjects none complained of pain during and immediately after surgery with no bleeding at any stage of theprocedure. By the end of 3rd day post operative most subjects reported no pain and swelling and very few subjects hadnegligible pain and swelling when evaluated. On subsequent follow-up of 1,2 and 4 week(s) none of the subject reportedof pain, swelling or bleeding and it was noted that all the areas treated with laser had healed without scarring with nosigns of recurrence. Fibrosis was seen in two male patients and one female patient treated for OL and OLP respectively.Conclusion: Patient compliance and contentment without any postoperative complications were observed to be of highdegree in the present study. Thus diode laser can be considered as a best alternative to conventional surgical treatmentmodality in managing OL and OLP and preventing its further transformation.}, keywords = {Diode laser,Oral leukoplakia,Oral lichen planus,potentially malignant lesions,Prevention}, url = {https://journal.waocp.org/article_80075.html}, eprint = {https://journal.waocp.org/article_80075_f2f7abd7cb326420e8e4a9c4b33f5172.pdf} }