@article { author = {Quach, Duc Trong and Vilaichone, Ratha-korn and Vu, Khien Van and Yamaoka, Yoshio and Sugano, Kentaro and Mahachai, Varocha}, title = {Helicobacter pylori Infection and Related Gastrointestinal Diseases in Southeast Asian Countries: An Expert Opinion Survey}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {19}, number = {12}, pages = {3565-3569}, year = {2018}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {10.31557/APJCP.2018.19.12.3565}, abstract = {Background: Helicobacter pylori (H. pylori) infection is currently considered as an infectious disease irrespective ofsymptoms and stage of disease. This study aimed to survey the impact of H. pylori infection and the current managementapproaches in Southeast Asian countries. Materials and methods: This is a survey among 26 experts from 9 SoutheastAsian countries (Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand and Vietnam),who attended a meeting to develop the ASEAN consensus on H. pylori management in November 2015. Results: Theprevalence of H. pylori varied significantly from 20% to 69% among countries, highest in Myanmar and lowest inMalaysia. The rate of H. pylori infection in patients with gastritis, peptic ulcer disease and gastric cancer (GC) alsovaried significantly, not only among countries but also among regions within the same country. The most commonmethod for H. pylori diagnosis before treatment was rapid urease test, followed by urea breath test. In multi-ethniccountries, some ethnic groups including Chinese, Batak and Minahasanese were considered as having higher risk ofGC. There have been no national screening programs for GC in all countries, and a majority of patients with GC werediagnosed in advanced stages with very poor 5-year survival. Conclusions: The prevalence of H. pylori infection andits infection rates in related gastrointestinal diseases were significantly different among Southeast Asian countries. Theprognosis of patients with GC in the region was very poor. The result of this survey is a platform for future internationaland regional research collaboration.}, keywords = {Helicobacter pylori,Gastritis,peptic ulcer disease,Gastric cancer,Southeast Asia}, url = {https://journal.waocp.org/article_80143.html}, eprint = {https://journal.waocp.org/article_80143_9595c87bc0bd96f8afb13e60703b2e0d.pdf} }