@article { author = {Jaafari-Ashkavandi, Zohreh and Khademi, Bijan and Malekzadeh, Mahyar and Shahmoradi, Zeinab}, title = {Serum Levels of Zinc, Copper and Ferritin in Patients with Salivary Gland Tumors}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {20}, number = {2}, pages = {545-548}, year = {2019}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {10.31557/APJCP.2019.20.2.545}, abstract = {Background: Variation in serum levels of trace elements including zinc, copper and ferritin has been reported incancer patients. The aim of this study was to evaluate these trace elements in the patients’ sera with benign and malignantsalivary gland tumors (SGTs) and compare them with normal individuals. Methods: In this cross-sectional study, 60patients with SGTs including 16 pleomorphic adenoma and 44 malignant SGTs, as well as 28 healthy controls, wereenrolled. Serum levels of zinc, copper and ferritin were determined by atomic absorption and ELISA methods. Datawere analyzed using one way ANOVA, Chi-square, Kruskal-Wallis and Mann- Whitney tests. Results: The meanconcentration of zinc, copper, ferritin was1.5± 2 ppm, 1.2± 0.5 ppm, and 96.7± 65.7 ng/ml in PA, 1.5± 1.4,1.3± 0.4,and 111.2± 112 in malignant SGTs, and1.1±0.3, 1.2± 0.23 and 124±135.8 in normal control groups. There was nostatistically significant difference between the patients and control groups, and between benign and malignant SGTs(P>0.05). Conclusion: The serum levels of trace elements in SGTs were not different from normal individuals. Theresults might have been affected by some interventional factors. Therefore, designing cohort complementary studiesmight result in obtaining more accurate data.}, keywords = {zinc,copper,Ferritin,Salivary Gland,Tumor}, url = {https://journal.waocp.org/article_81698.html}, eprint = {https://journal.waocp.org/article_81698_d2d2bf9ba9f51834589e06e374923879.pdf} }