@article { author = {Froidevaux, Laurel and Fiorini-Bernasconi, Cristina and Campiche, Valérie and Gehri, Mario and Jacto-Guillarmod, Martine and Crisinel, Pierre}, title = {School-based HPV Vaccination: Variation in Inter-school Vaccine Uptake not Influenced by the Introduction of a New Information Brochure}, journal = {Asian Pacific Journal of Cancer Prevention}, volume = {24}, number = {1}, pages = {249-255}, year = {2023}, publisher = {West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter.}, issn = {1513-7368}, eissn = {2476-762X}, doi = {10.31557/APJCP.2023.24.1.249}, abstract = {Background: Switzerland, with an adolescent HPV vaccination coverage at 59%, remains far from reaching the crucial swiss national goal of 80% coverage. Our objective was to implement a new information brochure in schools to increase HPV vaccination uptake. Methods: We designed a public health quality project. A new information brochure was produced and was distributed to a test group of 9th grade students from the Canton of Vaud, in Switzerland during the 2019-2020 school year. Vaccine uptake of the test group was compared to those of all other students in 2019-2020 and of students in the same schools in 2017-2018. Results: 12,143 electronic records were analyzed. 713 students were enrolled in 6 schools where the new brochure was distributed. Median age was 13 years (IQR 12-13), and 6,031 (49.7%) were female. Vaccine uptake was 52% (6,299/12,143). The new brochure did not result in increased uptake. Age ≥ 13 years (aOR 1.39, 95% CI 1.22-1.58) was significantly associated with uptake. Uptake increased between 2017-2018 (51%, 3,216/6,307) and 2019-2020 (52.8%, 3,083/5,836, p=0.04) due to increased acceptance among boys. The only determinant of uptake in 2019-2020 was uptake in the same schools in 2017-2018. Conclusion: The introduction of a new information brochure was insufficient to increase HPV vaccination coverage. More innovative strategies are needed.}, keywords = {human papillomavirus,HPV vaccines,preventive health services,Vaccine uptake,Vaccine hesitancy}, url = {https://journal.waocp.org/article_90458.html}, eprint = {https://journal.waocp.org/article_90458_fb18dbe81f0e723f1d8ed4354140308c.pdf} }