%0 Journal Article %T Physical Inactivity, Water Intake and Constipation as Risk Factors for Colorectal Cancer among Adults in Jordan %J Asian Pacific Journal of Cancer Prevention %I West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. %Z 1513-7368 %D 2013 %\ 09/01/2013 %V 14 %N 9 %P 5207-5212 %! Physical Inactivity, Water Intake and Constipation as Risk Factors for Colorectal Cancer among Adults in Jordan %K colorectal cancer %K physical activity %K Water intake %K Constipation %R %X Background: Physical activity has been found to play a role in cancer prevention. The purpose of this matchedcase-control study was to investigate the association between physical activity levels, water intake, constipationand colorectal cancer (CRC). Materials and Methods: Two hundred and thirty-two patients diagnosed withCRC (125 male, 107 female) were enrolled in this case-control study. Cases were matched to 271 populationcontrols (137 male, 134 female). Results: Drinking more than 4 cups of water daily decreased the risk of CRC by33-42%; however, this effect was non-significant. Having constipation was found to be a significant risk factorfor developing CRC with an OR=6.284 (95%CI=2.741-14.40). With reference to sedentary behavior, minimumactivity (600-3000 Metabolic Equivalents Task (MET)) had 43% protection against CRC and the level of HealthEnhancing Physical Activity OR was 0.58 (at 95%CI; 0.37-0.92). A significant negative association was foundbetween CRC and physical activity levels expressed as both METs and MET-hours/week (p for trend=0.017 and0.03, respectively). Among females, a significant trend of reduction in CRC by 62% was observed with increasingthe level of physical activity expressed in MET (p for trend=0.04). Conclusions: The risk of CRC may be reducedby adopting a healthy lifestyle and practicing physically activity regularly, especially among females. Consumingadequate amounts of water and healthy bowel motility could also reduce the risk of CRC. %U https://journal.waocp.org/article_28100_dc7572bfa939b648ae1498f2e4e23b71.pdf