%0 Journal Article %T Knowledge and Awareness of Human Papillomavirus (HPV), Cervical Cancer and HPV Vaccine among Women in Two Distinct Nepali Communities %J Asian Pacific Journal of Cancer Prevention %I West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. %Z 1513-7368 %D 2014 %\ 12/01/2014 %V 15 %N 19 %P 8287-8293 %! Knowledge and Awareness of Human Papillomavirus (HPV), Cervical Cancer and HPV Vaccine among Women in Two Distinct Nepali Communities %K HPV %K HPV vaccine %K cervical cancer %K Nepal %K Rural Communities %R %X Background: This study assessed human papillomavirus (HPV), cervical cancer, and HPV vaccine knowledgeand awareness among women in two sub-populations in Nepal - Khokana, a traditional Newari village in theLalitpur District about eight kilometers south of Kathmandu, and Sanphebagar, a village development committeewithin Achham District in rural Far-Western Nepal. Methods: Study participants were recruited during healthcamps conducted by Nepal Fertility Care Center, a Nepali non-governmental organization. Experienced staffadministered a Nepali language survey instrument that included questions on socio-demographics, reproductivehealth and knowledge on HPV, cervical cancer, and the HPV vaccine. Results: Of the 749 participants, 387 (51.7%)were from Khokana and 362 (48.3%) were from Sanphebagar. Overall, 53.3% (n=372) of women were awareof cervical cancer with a significant difference between Khokana and Sanphebagar (63.3% vs 43.0%; p=0.001).Overall, 15.4% (n=107) of women had heard of HPV and 32% (n=34) of these women reported having heard ofthe HPV vaccine. If freely available, 77.5% of the women reported willingness to have their children vaccinatedagainst HPV. Factors associated with cervical cancer awareness included knowledge of HPV (Khokana: OddsRatio (OR)=24.5; (95% Confidence Interval (CI): 3.1-190.2, Sanphebagar: OR=14.8; 95% CI: 3.7-58.4)) andsexually transmitted infections (Khokana: OR=6.18; 95% CI: 3.1-12.4; Sanphebagar: OR=17.0; 95% CI: 7.3-39.7) among other risk factors. Conclusions: Knowledge and awareness of HPV, cervical cancer, and the HPVvaccine remains low among women in Khokana and Sanphebagar. Acceptance of a freely available HPV vaccinefor children was high, indicating potentially high uptake rates in these communities. %U https://journal.waocp.org/article_29915_380bc75d916e9817cccc755b7003c594.pdf