%0 Journal Article %T Glioma Epidemiology in the Central Tunisian Population: 1993-2012 %J Asian Pacific Journal of Cancer Prevention %I West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. %Z 1513-7368 %D 2014 %\ 12/01/2014 %V 15 %N 20 %P 8753-8757 %! Glioma Epidemiology in the Central Tunisian Population: 1993-2012 %K Glioma %K Epidemiology %K Incidence %K Tunisia %K Trends %R %X Background: Glioma is a heterogeneous central nervous system (CNS) tumor group that encompassesdifferent histological subtypes with high variability in prognosis. The lesions account for almost 80% of primarymalignant brain tumors. The aim of this study is to extend our understanding of the glioma epidemiology in thecentral Tunisian region. Materials and Methods: We analyzed 393 gliomas recorded in cancer registry of centralTunisia from 1993 to 2012. Crude incidence rates (CR) and world age-standardized rates (ASR) were estimatedusing annual population data size and age structure. Statistic correlations were established using Chi-square andKaplan-Meier test. Results: Tunisian glioma patients were identified with a mean age at diagnosis of 48 yearsand 1.5 sex ratio (male/female). During the 19 years period of study the highest incidence value was observedin male group between 1998 and 2002 (CR: 0.28, ASR: 0.3). Incidence results underline increasing high gradeglioma occurring in the adulthood in the last period (2007-2012). Median survival was 27 months, with 1-, 2-and 5-year survival rates of 42%, 30% and 26%, respectively. Survival was greater in patients with youngerage, lower tumor grade, infratentrial tumor location and undergoing a palliative treatment. Conclusions: Thiscentral Tunisia gliomas registry study provides important information that could improve glioma managementand healthcare practice. %U https://journal.waocp.org/article_29990_9d949b62c932da489d3381d80202f65e.pdf