%0 Journal Article %T Efficacy of Bifidobacterium Tetragenous Viable Bacteria Tablets for Cancer Patients with Functional Constipation %J Asian Pacific Journal of Cancer Prevention %I West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. %Z 1513-7368 %D 2014 %\ 12/01/2014 %V 15 %N 23 %P 10241-10244 %! Efficacy of Bifidobacterium Tetragenous Viable Bacteria Tablets for Cancer Patients with Functional Constipation %K Functional constipation %K Bifidobacterium tetragenous viable bacteria tablets %K Efficacy %K cancer patients %R %X Objective: To investigate the efficacy and side effects of Bifidobacterium tetragenous viable bacteria tablets intreating cancer patients with functional constipation during chemotherapy. Methods: A consecutive cohort of100 cancer patients with functional constipation were divided into two equal groups: patients in the experimentalgroup were given Bifidobacterium tetragenous viable bacteria tablets combined with chemotherapy, while patientsin the control group received chemotherapy alone. After 4 weeks, the efficacy and side effects in treating functionalconstipation were evaluated. Results: Constipation in 48 patients in experimental group was controlled (9returned to normal), with a total response rate of 96%, and 1 patient reported diarrhea (2%). In contrast only16 patients in the control group demonstrated improvement and 34 were still constipated after chemotherapy,with a response rate of 32%. The difference in response rate was statistically significant (P <0.05). Conclusion:This study suggested that Bifidobacterium tetragenous viable bacteria tablets are effective and safe in treatingcancer patients with functional constipation during chemotherapy. %U https://journal.waocp.org/article_30250_d288c3049ed68e81bcccb81027856e54.pdf