%0 Journal Article %T Elastography for Breast Cancer Diagnosis: a Useful Tool for Small and BI-RADS 4 Lesions %J Asian Pacific Journal of Cancer Prevention %I West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. %Z 1513-7368 %D 2014 %\ 12/01/2014 %V 15 %N 24 %P 10739-10743 %! Elastography for Breast Cancer Diagnosis: a Useful Tool for Small and BI-RADS 4 Lesions %K Ultrasound %K Elastography %K breast lesions %K strain ratio %R %X The present study aimed at evaluating and comparing the diagnostic performance of B-mode ultrasound (US),elastography score (ES), and strain ratio (SR) for the differentiation of breast lesions. This retrospective studyenrolled 431 lesions from 417 in-hospital patients. All patients were examined with both conventional ultrasoundand elastography. Two experienced radiologists reviewed ultrasound and elasticity images. The histopathologicresult obtained from ultrasound-guided core biopsy or operation excisions were used as the reference standard.Pathologic examination revealed 276 malignant lesions (64%) and 155 benign lesions (36%). A cut-off pointof 4.15 (area under the curve, 0.891) allowed significant differentiation of malignant and benign lesions. ROC(receiver-operating characteristic) curves showed a higher value for combination of B-mode ultrasound andelastography for the diagnosis of breast lesions. Conventional ultrasound combined elastography showed highsensitivity, specificity, and accuracy for group II lesions (10mm