%0 Journal Article %T Virtual Non-Contrast Computer Tomography (CT) with Spectral CT as an Alternative to Conventional Unenhanced CT in the Assessment of Gastric Cancer %J Asian Pacific Journal of Cancer Prevention %I West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. %Z 1513-7368 %D 2015 %\ 06/01/2015 %V 16 %N 6 %P 2521-2526 %! Virtual Non-Contrast Computer Tomography (CT) with Spectral CT as an Alternative to Conventional Unenhanced CT in the Assessment of Gastric Cancer %K gastric carcinoma %K gemstone spectral imaging %K virtual non-contrast %K contrast-to-noise ratio %K perigastric fat %R %X Objective: The purpose of this study was to evaluate computed tomography (CT) virtual non-contrast (VNC)spectral imaging for gastric carcinoma. Materials and Methods: Fifty-two patients with histologically provengastric carcinomas underwent gemstone spectral imaging (GSI) including non-contrast and contrast-enhancedhepatic arterial, portal venous, and equilibrium phase acquisitions prior to surgery. VNC arterial phase (VNCa),VNC venous phase (VNCv), and VNC equilibrium phase (VNCe) images were obtained by subtracting iodinefrom iodine/water images. Images were analyzed with respect to image quality, gastric carcinoma-intragastricwater contrast-to-noise ratio (CNR), gastric carcinoma-perigastric fat CNR, serosal invasion, and enlargedlymph nodes around the lesions. Results: Carcinoma-water CNR values were significantly higher in VNCa,VNCv, and VNCe images than in normal CT images (2.72, 2.60, 2.61, respectively, vs 2.35, p≤0.008). Carcinomaperigastricfat CNR values were significantly lower in VNCa, VNCv, and VNCe images than in normal CTimages (7.63, 7.49, 7.32, respectively, vs 8.48, p< 0.001). There were no significant differences of carcinoma-waterCNR and carcinoma-perigastric fat CNR among VNCa, VNCv, and VNCe images. There was no difference inthe determination of invasion or enlarged lymph nodes between normal CT and VNCa images. Conclusions:VNC arterial phase images may be a surrogate for conventional non-contrast CT images in gastric carcinomaevaluation. %U https://journal.waocp.org/article_30769_2f981ce54067c5a2236c0335b6b24722.pdf