%0 Journal Article %T RASSF1A Gene Methylation is Associated with Nasopharyngeal Carcinoma Risk in Chinese %J Asian Pacific Journal of Cancer Prevention %I West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. %Z 1513-7368 %D 2015 %\ 06/01/2015 %V 16 %N 6 %P 2283-2287 %! RASSF1A Gene Methylation is Associated with Nasopharyngeal Carcinoma Risk in Chinese %K RASSF1A %K Nasopharyngeal carcinoma %K methylation %R %X In order to explore the association between RASSF1A methylation and nasopharyngeal carcinoma (NPC)risk of Chinese, we carried out a meta-analysis with searches of PubMed, Web of Science, ProQest and Medlinedatabases. Ultimately, 14 articles were identified and analysised using R Software (R version 3.1.2) includingmeta packages. Overall, we found a significant relationship between RASSF1A methylation and NPC risk (OR30.7; 95 % CI, 16.71~56.23; z=11.0591; p<0.0001) in a fixed effects model and (OR 32.1; 95% CI, 14.27~72.01;z=8.3984; p<0.0001) in a random effects model pooled. In tissue and NP brushings groups , similar results werefound. Hence, our study identified a strong association between RASSF1A methylation and NPC and highlighteda promising potential for RASSF1A methylation in NPC risk prediction of Chinese. %U https://journal.waocp.org/article_30793_2d69f0274d628d9237559f75c59fa5b5.pdf