%0 Journal Article %T Effects of Tobacco Smoking on the Dorsum of the Tongue and Buccal Epithelium %J Asian Pacific Journal of Cancer Prevention %I West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. %Z 1513-7368 %A Al Shammari, Abdullah Faraj %A AL Ibrahim, Ibrahim Khalil %A Alaauldeen, Amjad Ibrahim %A Merza, Randa Fouad %A Ahmed, Hussain Gadelkarim %D 2016 %\ 10/01/2016 %V 17 %N 10 %P 4713-4718 %! Effects of Tobacco Smoking on the Dorsum of the Tongue and Buccal Epithelium %R 10.22034/APJCP.2016.17.10.4713 %X   Objective: The aim of this study was to assess the effects of tobacco smoking on the dorsum of the tongue and buccal epithelium. Methodology: This case control cross-sectional study was conducted with 174 smoking and non-smoking volunteers living in the city of Hail, Northern KSA. Cytological Materials were obtained from buccal mucosa and dorsum of the tongue, and assessed using cytopathological methods. Results: In buccal smears, cytological atypia was observed in 17 out of 101 (16.8%) smoker cases but only 3/73(4.1%) of the controls. For cytological atypia in buccal and tongue smears, the adjusted odd ratio (OR) and the 95% confidence interval (CI) were found to be 4.7 (1.3-16.8), P < 0.016)) and 4.3 (0.93- 20.2), P <0.06)), respectively, in the two sites. Conclusion: Tobacco smoking is a major risk factor for occurrence of cytological atypia, which might subsequently develop into oral precancerous and cancerous lesions. Oral exfoliative cytology is an easy and cheap non-invasive procedure which appears highly suitable for screening populations at risk of developing oral cancer. %U https://journal.waocp.org/article_40513_e3ee90bd41ae4fb01afdcfa7cb0776ea.pdf