%0 Journal Article %T Survival Time and Prognostic Factors for Breast Cancer among Women in North-East Peninsular Malaysia %J Asian Pacific Journal of Cancer Prevention %I West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. %Z 1513-7368 %A Nordin, Noorfariza %A Yaacob, Najib Majdi %A Abdullah, Noor Hashimah %A Mohd Hairon, Suhaily %D 2018 %\ 02/01/2018 %V 19 %N 2 %P 497-502 %! Survival Time and Prognostic Factors for Breast Cancer among Women in North-East Peninsular Malaysia %K breast cancer %K Prognostic factor %K Survival time %K Malaysian Women %R 10.22034/APJCP.2018.19.2.497 %X Background: Breast cancer is the most common malignant disease and the leading cause of cancer death amongwomen globally. This study aimed to determine the median survival time and prognostic factors for breast cancerpatients in a North-East State of Malaysia. Methods: This retrospective cohort study was conducted from January tillApril 2017 using secondary data obtained from the state’s cancer registry. All 549 cases of breast cancer diagnosedfrom 1st January 2007 until 31st December 2011 were selected and retrospectively followed-up until 31st December2016. Sociodemographic and clinical information was collected to determine prognostic factors. Results: The average(SD) age at diagnosis was 50.4 (11.2) years, the majority of patients having Malay ethnicity (85.8%) and a histology ofductal carcinoma (81.5%). Median survival times for those presenting at stages III and IV were 50.8 (95% CI: 25.34,76.19) and 6.9 (95% CI: 3.21, 10.61) months, respectively. Ethnicity (Adj. HR for Malay vs non-Malay ethnicity=2.52;95% CI: 1.54, 4.13; p<0.001), stage at presentation (Adj. HR for Stage III vs Stage I=2.31; 95% CI: 1.57, 3.39; p<0.001and Adj. HR for Stage IV vs Stage I=6.20; 95% CI: 4.45, 8.65; p<0.001), and history of surgical treatment (Adj. HRfor patients with no surgical intervention=1.95; 95% CI: 1.52, 2.52; p<0.001) were observed to be the statisticallysignificant prognostic factors associated with death caused by breast cancer. Conclusion: The median survival timeamong breast cancer patients in North-East State of Malaysia was short as compared to other studies. Primary andsecondary prevention aimed at early diagnosis and surgical management of breast cancer, particularly among the Malayethnic group, could improve treatment outcome. %U https://journal.waocp.org/article_55258_8d51fb354f1944e8e40733b7ac5a4ea5.pdf