%0 Journal Article %T Alcohol Consumption as a Risk Factor for Breast Cancer Development: A Case-Control Study in Brazil %J Asian Pacific Journal of Cancer Prevention %I West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. %Z 1513-7368 %A Vieira, Roberto %A Tobar, Juan Sebastián Sánchez %A Dardes, Rita %A Santos Thuler, Luiz Claudio %D 2018 %\ 03/01/2018 %V 19 %N 3 %P 703-707 %! Alcohol Consumption as a Risk Factor for Breast Cancer Development: A Case-Control Study in Brazil %K breast cancer %K alcohol consumption %K risk %K Brazilian women %R 10.22034/APJCP.2018.19.3.703 %X Background: Alcohol consumption is a well-established risk factor for breast cancer, but the evidence is mostlyfrom developed countries. Brazil is going through a rapid demographic expansion, and studies of this relationship arealso needed in such unexplored settings. Methods: We assessed the relationship between alcohol consumption andbreast cancer risk among 1,506 Brazilian women (406 cases and 1,100 controls). Regression models were used tocalculate odds ratios (OR) and 95% confidence intervals (CI). All statistical tests were two-tailed. Results: The meanage of the 1,506 women was 42.0 (standard deviation, ±15.0) years. There was a significant association between breastcancer and age, body mass index, age at menarche, menstrual flow and menstrual cycle. Multivariate analysis showedan increased risk of invasive breast cancer in regular alcohol consumers (years old: OR 3.9; 95% CI 1.2–13.4) compared with abstainers or occasional drinkers. Women with a regular alcoholintake for 10 years or more who were less than 50 years old had a threefold higher risk of developing breast cancer(OR 3.0; 95% CI 1.2–7.6). Conclusion: Regular alcohol consumption increases the risk of breast cancer mainly amongwomen less than 50 years old. %U https://journal.waocp.org/article_57881_9c8a9d0b6975b5c5048f37f233856b46.pdf