%0 Journal Article %T Five-Year Overall Survival of Interval Breast Cancers is Better than Non- Interval Cancers from Korean Breast Cancer Registry %J Asian Pacific Journal of Cancer Prevention %I West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. %Z 1513-7368 %A Lee, Jung Sun %A Kim, Hyun-Ah %A Cho, Se-Heon %A Lee, Han-Byoel %A Park, Min Ho %A Jeong, Joon %A Park, Heung Kyu %A Oh, Minkyung %A Yi, Onvox %D 2019 %\ 06/01/2019 %V 20 %N 6 %P 1717-1726 %! Five-Year Overall Survival of Interval Breast Cancers is Better than Non- Interval Cancers from Korean Breast Cancer Registry %K Breast Neoplasm %K Early Detection of Cancer %K mammography %K Health care Disparities %K Prognosis %R 10.31557/APJCP.2019.20.6.1717 %X Objective: Interval breast cancer (IC) is a limitation of breast cancer screening. We investigated data from alarge scaled breast cancer dataset of patients with breast cancer who underwent breast cancer screening in order torecapitulate the overall survival (OS) of patients with ICs compared to those with non-ICs. Methods: A total of 27,141patients in the Korean breast cancer registry with breast cancer who had ever participated in biannual national breastcancer screening programs between 2009 and 2013 were enrolled. We compared the social, pregnancy-associated, andpathologic characteristics between the IC and non-IC groups and identified the significant prognostic factors for OS.Results: The proportion of ICs was 1.3% (370/27,141) in this study population. ICs were correlated with age 45-55years at diagnosis, higher levels of education, early menopause (provinces (Kangwon, Kyungnam, Jeju, and Dae-jeon), and family history of breast cancer. Low-to-intermediate nucleargrade, early stage (stage 0-I), and low Ki-67 level were also correlated with IC proportion. Non-ICs were associatedwith an increased risk of five-year mortality (hazard ratio [HR] 7.4; 95% confidence interval [CI]:1.85-29.66; p = 0.005)compared to ICs. Lymph node metastasis, residence (Kyung-nam province), low education status, high histologic grade,and asymptomatic cancers increased the HR of five-year OS. Conclusion: ICs occurred unequally in specific provinceand relatively high-educated women in Korea. They were also diagnosed with early-stage breast cancer with a favorablerecurrence risk, and their outcome was better than those of patients with other breast cancers in breast cancer screening. %U https://journal.waocp.org/article_88587_7644cf57f404f224aaa595e1df5deda2.pdf