TY - JOUR ID - 25457 TI - Myeloid Antigen Positivity in Turkish Children With Acute Lymphoblastic Leukemia Lacks Influence on Prognosis JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 Y1 - 2010 PY - 2010 VL - 11 IS - 6 SP - 1823 EP - 1826 KW - Acute Lymphoblastic Leukemia KW - myeloid antigen KW - childhood DO - N2 - Introduction: Several studies have suggested that the presence of myeloid antigens is a poor prognostic factorin patients with acute lymphoid leukemia (ALL). Objective: We aimed to assess this possibility in Turkish patients.Materials and Methods: Seventy-three children with a diagnosis of ALL-L1 and 38 with ALL-L2 were included.Flow cytometry and fluorescein-isothiocynate conjugated antibodies were used to determined surface antigens onblasts. Results: Myeloid antigens were positive in 48.4% with ALL-L1 and 60.5% with ALL-L2, the differencenot being significant. Overall survival rates of myeloid antigen positive patients at 36, 60, and 72 months were76%, 58%, and 48%, respectively, comparable to the corresponding 70%, 56%, and 46% in myeloid antigennegative patients (p >0.05). Conclusion: We did not find any association between myeloid antigen positivity andclinical and laboratory features of ALL. UR - https://journal.waocp.org/article_25457.html L1 - https://journal.waocp.org/article_25457_fbaf464dbeeb6249c65202a23aaceedd.pdf ER -