TY - JOUR ID - 25463 TI - Hormone Receptor Status of Operable Breast Cancers in Indonesia: Correlation with Other Prognostic Factors and Survival JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 Y1 - 2006 PY - 2006 VL - 7 IS - 2 SP - 321 EP - 324 KW - Breast cancer – KW - prognostic factor – KW - estrogen receptor – KW - Progesterone Receptor DO - N2 - Objective: The aim of this study was to evaluate the hormone receptor status of operable breast cancers inYogyakarta, Indonesia , and its correlation with other established prognostic factors and overall survival. Materialsand Methods: Operable breast cancers in Yogyakarta were studied clinically, pathologically andimmunohistochemically for tumor size, lymph node status, histological grade, mitotic index, ER, PR, c-erbB2, p53and MIB-1 proliferation index. Correlations of ER and PR with those prognostic factors were determined, andpatients were longitudinally followed for overall survival. Results: Breast cancer showed an aggressive phenotypewith large tumor size, positive lymph nodes, high histologic grade, high mitotic index, positive c-erbB2, p53 andMIB- 1 proliferation index. Positive ER and PR did not improve the prognosis significantly, and adjuvant treatmentwith tamoxifen did not increase overall survival. UR - https://journal.waocp.org/article_25463.html L1 - https://journal.waocp.org/article_25463_973499a8cf6370a9bfb069eb4e7ea31a.pdf ER -