TY - JOUR ID - 26488 TI - Ornithine Decarboxylase: A Promising and Exploratory Candidate Target for Natural Products in Cancer Chemoprevention JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 Y1 - 2012 PY - 2012 VL - 13 IS - 5 SP - 2425 EP - 2427 KW - Ornithine decarboxylase KW - molecular target KW - Natural products KW - cancer chemoprevention DO - N2 - Ornithine decarboxylase (ODC), the first enzyme in the polyamine biosynthesis, plays an important role intumor progression, cell proliferation and differentiation. In recent years, ODC has been the subject of intensestudy among researchers, as a target for anti-cancer therapy and specific inhibitory agents, have the potentialto suppress carcinogenesis and find applications in clinical therapy. In particular, it is suggested that ODC is apromising candidate target for natural products in cancer chemoprevention. Future exploration of ornithinedecarboxylase inhibitors present in nature may offer great hope for finding new cancer chemopreventive agents. UR - https://journal.waocp.org/article_26488.html L1 - https://journal.waocp.org/article_26488_a484c5bd4969f93bff9a458d15564c6d.pdf ER -