TY - JOUR ID - 28561 TI - Levels of Serum 25-Hydroxy-Vitamin D in Benign and Malignant Breast Masses JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 Y1 - 2014 PY - 2014 VL - 15 IS - 1 SP - 129 EP - 132 KW - Breast Neoplasm KW - breast mass KW - cancer KW - Vitamin D KW - 25(OH)-vitamin D DO - N2 - Background: The true association between breast cancer and vitamin D is currently under investigation.We compared serum 25-hydroxy-vitamin D levels in women with benign and malignant breast masses andcontrols. Materials and Methods: Levels of vitamin D were measured by electrochemiluminescense. Serum levels>35 ng/ml, 25-35 ng/ml, 12.5-25 ng/ml and <12.5 ng/ml were considered as normal, mild, moderate and severevitamin D deficiency, respectively. Results: Overall, 364 women were included in the control, 172 in the benignand 136 in the malignant groups. The median serum vitamin D level was significantly lower in breast cancersthan controls. Levels were also lower in malignant than benign cases and in benign cases than controls althoughstatistically non-significant. Conclusions: Multinomial logistic regression analysis showed that severe vitamin Ddeficiency causes a three-fold increase in the risk of breast cancer while this was not the case for moderate andmild deficiency. UR - https://journal.waocp.org/article_28561.html L1 - https://journal.waocp.org/article_28561_b6b315dc103fc03b445088bcdfa0cd54.pdf ER -