TY - JOUR ID - 28594 TI - Treatment and Outcomes of Ewing Sarcoma in Turkish Adults: A Single Centre Experience JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 Y1 - 2014 PY - 2014 VL - 15 IS - 1 SP - 327 EP - 330 KW - Adult cases KW - Ewing sarcoma KW - Prognosis KW - Turkey DO - N2 - Background: Ewing sarcoma is a small round cell tumor arising from soft tissue and bone that predominantlyaffects children and adolescents. The most unfavorable prognostic factor is the presence of distant metastasis atthe time of diagnosis. Materials and Methods: The records of 26 Ewing sarcoma patients (14 male, 12 female)were re-evaluated retrospectively. Results: The median age was 26.5 (19-42) years. Eight patients (31%) showed aprimary tumor in their extremities, 8 (31%) in the thorax, 4 (15%) at the vertebra, 4 (15%) in the head and neck,and 2 (8%) in the abdomen. Five patients (19%) had distant metastasis at diagnosis. The median progression-freesurvival was 72 months and 10 months in localized and metastatic disease, respectively (p=0.005). The overallsurvival rate was 19 months in metastatic disease, and the 5-year overall survival rate was 64% in localizeddisease (p=0.006). Patients who had localized disease in the extremities and were under age 30 had a favorableprognosis. Conclusions: Although Ewing sarcoma is a tumor affecting children and adolescents, it may be seenin adults, where the prognosis is generally worse. Although it is a highly malignant tumor, it is possible to achieveimproved survival with combined modality treatments. UR - https://journal.waocp.org/article_28594.html L1 - https://journal.waocp.org/article_28594_5685feb5c1dd6cf53485330bc6ac8386.pdf ER -