TY - JOUR ID - 29934 TI - Clinical Applicability of Multi-Tumor Marker Protein Chips for Diagnosing Ovarian Cancer JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 Y1 - 2014 PY - 2014 VL - 15 IS - 19 SP - 8409 EP - 8411 KW - Protein chip KW - Tumor markers KW - Ovarian cancers KW - treatment evaluation DO - N2 - Purpose: To assess the value of multi-tumor marker protein chips in the diagnosis and treatment of ovariancancer. Materials and Methods: Twelve tumor markers (CA19-9, NSE, CEA, CA242, CK19, β-HCG, AFP, SCC,c-PSA, CA125, CA724 and CA15-3) were detected by protein biochip in 220 patients with ovarian carcinomas,205 with benign ovarian tumors and 200 healthy subjects. Results: The positivity rate was obviously higher inovarian cancer (77.7%), than that in the benign cases (26.3%, p<0.01) and healthy subjects (4.5%, p<0.01). Serumlevels of tumor markers were furthermore significantly higher in cases with lymph node metastasis (86.8%) thanthose without metastasis (44.7%), p<0.01. Conclusions: Multi-tumor marker protein chips provide importantassistance in the diagnosis and treatment evaluation in ovarian cancers. UR - https://journal.waocp.org/article_29934.html L1 - https://journal.waocp.org/article_29934_b3a714177e3c40d7aa53055eb236dc22.pdf ER -