TY - JOUR ID - 30250 TI - Efficacy of Bifidobacterium Tetragenous Viable Bacteria Tablets for Cancer Patients with Functional Constipation JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 Y1 - 2014 PY - 2014 VL - 15 IS - 23 SP - 10241 EP - 10244 KW - Functional constipation KW - Bifidobacterium tetragenous viable bacteria tablets KW - Efficacy KW - cancer patients DO - N2 - Objective: To investigate the efficacy and side effects of Bifidobacterium tetragenous viable bacteria tablets intreating cancer patients with functional constipation during chemotherapy. Methods: A consecutive cohort of100 cancer patients with functional constipation were divided into two equal groups: patients in the experimentalgroup were given Bifidobacterium tetragenous viable bacteria tablets combined with chemotherapy, while patientsin the control group received chemotherapy alone. After 4 weeks, the efficacy and side effects in treating functionalconstipation were evaluated. Results: Constipation in 48 patients in experimental group was controlled (9returned to normal), with a total response rate of 96%, and 1 patient reported diarrhea (2%). In contrast only16 patients in the control group demonstrated improvement and 34 were still constipated after chemotherapy,with a response rate of 32%. The difference in response rate was statistically significant (P <0.05). Conclusion:This study suggested that Bifidobacterium tetragenous viable bacteria tablets are effective and safe in treatingcancer patients with functional constipation during chemotherapy. UR - https://journal.waocp.org/article_30250.html L1 - https://journal.waocp.org/article_30250_d288c3049ed68e81bcccb81027856e54.pdf ER -