TY - JOUR ID - 32241 TI - Inhibitory Effects of Gallic Acid Isolated from Caesalpinia mimosoides Lamk on Cholangiocarcinoma Cell Lines and Foodborne Pathogenic Bacteria JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 AU - Rattanata, Narintorn AU - Klaynongsruang, Sompong AU - Daduang, Sakda AU - Tavichakorntrakool, Ratree AU - Limpaiboon, Temduang AU - Lekphrom, Ratsami AU - Boonsiri, Patcharee AU - Daduang, Jureerut AD - Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen, Thailand AD - Y1 - 2016 PY - 2016 VL - 17 IS - 3 SP - 1341 EP - 1345 DO - N2 - Gallic acid was isolated from Caesalpinia mimosoides Lamk and the structure s identified based on spectroscopic analysis and comparison with authentic compound. In this study we compared the ability of natural gallic acid (nGA) and commercial gallic acid (cGA) to inhibit the proliferation of cholangiocarcinoma cell lines (M213, M214) and foodborne pathogenic bacteria (Salmonella spp. and Plesiomonas shigelloides). Both nGA and cGA had the same inhibitory effects on cell proliferation by inducing apoptosis of cholangiocarcinoma cell lines. In addition, nGA inhibited growth of foodborne pathogenic bacteria in the same manner as cGA. Our results suggest that nGA from Caesalpinia mimosoides Lamk is a potential anticancer and antibacterial compound. However, in vivo studies are needed to elucidate the specific mechanisms involved. UR - https://journal.waocp.org/article_32241.html L1 - https://journal.waocp.org/article_32241_d8278c598109d469ad0176c5a0bef953.pdf ER -