TY - JOUR ID - 32259 TI - Investigating Preoperative Hematologic Markers for Prediction of Ovarian Cancer Surgical Outcome JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 AU - Ashrafganjoei, Tahereh AU - Mohamadianamiri, Mahdiss AU - Farzaneh, Farah AU - Hosseini, Maryam Sadat AU - Arab, Maliheh AD - Gyneco-Oncology, Preventative Gynecology Research Center (PGRC). Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran AD - Y1 - 2016 PY - 2016 VL - 17 IS - 3 SP - 1445 EP - 1448 DO - N2 - Purpose: The current study aimed at assessing the association between neutrophil-lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) for the prognosis of the surgical outcome of epithelial ovarian cancer (EOC). Materials and Methods: EOC patient medical records of surgical operations between January, 2005 and December, 2015 were reviewed and their data of clinicopathological complete blood counts (CBCs) and surgical outcomes were collected. To assess their effects on surgical outcomes, PLR and NLR optimal predictive values were determined and then compared with each other. Results: A statistically significant relation was found between surgical outcomes and NLR and PLR (p(PLR: 192,3,293; NLR: 3). The sensitivity and specificity were 0.74 and 0.67, respectively for PLR and 0.74 and 0.58, for NLR. Conclusions: NLR and PLR seem to be useful methods for the prediction of surgical outcomes in patients with EOCs. Increased NLR and PLR proved to be beneficial for poor surgical outcomes. Moreover, PLR increase showed further help in the predicting outcome of EOC suboptimal debulking. UR - https://journal.waocp.org/article_32259.html L1 - https://journal.waocp.org/article_32259_1c248842efe3a3168ce4525e73ab2016.pdf ER -