TY - JOUR ID - 32357 TI - Mean Platelet Volume as an Independent Predictive Marker for Pathologic Complete Response after Neoadjuvant Chemotherapy in Patients with Locally Advanced Breast Cancer JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 AU - Mutlu, Hasan AU - Eryılmaz, Melek Karakurt AU - Musri, Fatma Yalçcn AU - Gunduz, Seyda AU - Salim, Derya Kıvrak AU - Coskun, Hasan Senol AD - Department of Medical Oncology, Antalya Research and Training Hospital, Antalya, Turkey AD - Y1 - 2016 PY - 2016 VL - 17 IS - 4 SP - 2089 EP - 2092 DO - N2 - Background: The impact of mean platelet volume (MPV) on prognosis, diagnosis and response to therapy in cancer patients has been widely investigated. In the present study, we evaluated whether MPV at diagnosis has predictive value for pathologic complete response (pCR) after neoadjuvant chemotherapy in patients with locally advanced breast cancer (LABC). Materials and Methods: A total of 109 patients with LABC from Akdeniz University and Antalya Research and Training Hospital were evaluated retrospectively. Results: ROC curve analysis suggested that the optimum MPV cut-off point for LABC patients with pCR () was 8.15 (AUC:0.378, 95%CI [0.256- 0.499], p=0.077). The patients with MPV UR - https://journal.waocp.org/article_32357.html L1 - https://journal.waocp.org/article_32357_a58f2a1bf619622d4d453c797a5fae2e.pdf ER -