TY - JOUR ID - 33093 TI - Inverse Correlation between Cancer Size and Abdominal Obesity in Colorectal Cancer Cases JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 AU - Jeong, Taek Gun AU - Kim, Ji Wan AU - Lee, Sun-Young AU - Park, Hee Sun AU - Han, Hye Seung AU - Hwang, Dae Yong AD - Departments of Internal Medicine, Radiology, Pathology, and Surgery, Konkuk University School of Medicine, Seoul, Korea AD - Y1 - 2016 PY - 2016 VL - 17 IS - 8 SP - 4025 EP - 4030 DO - N2 - Background Correlation between colorectal cancer (CRC) and abdominal obesity has been established, but there is a paucity of data on non-obese CRC patients. The aim of this study was to establish the characteristics of CRCs that occur in such patients. Materials and Methods Consecutive CRC patients without cachexia were included. Unintended body weight loss, T4- or M1-staged CRCs, extensive lymph node involvement, or synchronous malignancy were classi ed as cachectic conditions. Abdominal fat volumes were measured using a multidetector CT unit with a software (Rapidia, INFINITT, Seoul, Korea). Results Of the newly-diagnosed CRC patients, 258 non-cachectic and 88 cachectic patients were analyzed. The cancer size (p<0.001) and T stage (p<0.001) were inversely correlated with body mass index (BMI), visceral fat and subcutaneous fat volumes. Cancer size was the only independent factor related to BMI (p0.016), visceral fat volume (p0.002), and subcutaneous fat volume (p0.027). In non-cachectic patients, a signi cant inverse correlation was found only between the cancer size and visceral fat volume (p0.017). Conclusions Non-obese CRC patients tend to have larger CRC lesions than their obese counterparts even under non-cachectic conditions. Such an inverse correlation between cancer size and visceral fat volume suggests that considerable CRCs are not correlated with abdominal obesity. UR - https://journal.waocp.org/article_33093.html L1 - https://journal.waocp.org/article_33093_db7d615aadd85207d51a920e4697d83e.pdf ER -