TY - JOUR ID - 77410 TI - Probably Benign Solid Breast Lesions on Ultrasound: Need for Biopsy Reassessed JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 AU - Fatima, Kulsoom AU - Masroor, Imrana AU - Khanani, Samina AD - Department of Radiology, Aga Khan University, Karachi, Pakistan. Y1 - 2018 PY - 2018 VL - 19 IS - 12 SP - 3467 EP - 3471 KW - Keywords: BI-RADS KW - probably benign KW - biopsy KW - Ultrasound DO - 10.31557/APJCP.2018.19.12.3467 N2 - Objective: To determine the negative predictive value of ultrasound for breast masses with probably benignmorphology, and to assess whether follow-up may be an acceptable alternative to biopsy. Methods: After InstitutionalReview Board approval, all solid breast masses categorized as probably benign (American College of Radiology BreastImaging Reporting and Data System [BI-RADS] 3) on ultrasound from January 2014 to December 2015, and havingeither tissue diagnosis or imaging stability for 24 months, or downgrading to BIRADS 2 during imaging surveillancewere included. Result: A total of 157 lesions in 40 patients constituted the study population. The mean patient age was31.3 years (range, 20-56 years). Seventeen of these 157 lesions underwent tissue diagnosis with no invasive breast cancer.Out of the remaining 140 lesions, 115 were stable on imaging for 24 months or more. The rest 25 were deemed benignbecause of decrease in size on follow up (n=1), non-recommendation of further imaging by the second radiologist onfollow up ultrasound (n= 13) or presence of benign tissue diagnosis in the largest lesion (n=11). Conclusion: Ultrasoundhas 100% negative predictive value for breast lesions with probably benign morphology, whether palpable or not.Follow up is an appropriate option to immediate biopsy of such lesions keeping in mind that noncompliance withsurveillance may be a potential problem. UR - https://journal.waocp.org/article_77410.html L1 - https://journal.waocp.org/article_77410_bf0e1505a770294ca29a31e067ba2092.pdf ER -