TY - JOUR ID - 80143 TI - Helicobacter pylori Infection and Related Gastrointestinal Diseases in Southeast Asian Countries: An Expert Opinion Survey JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 AU - Quach, Duc Trong AU - Vilaichone, Ratha-korn AU - Vu, Khien Van AU - Yamaoka, Yoshio AU - Sugano, Kentaro AU - Mahachai, Varocha AD - Department of Internal Medicine, University of Medicine and Pharmacy at Hochiminh City, Hochiminh, Vietnam. AD - Division of Gastroenterology, Department of Medicine, Thammasat University Hospital, Pathumthani, Thailand. AD - Department of Gastrointestinal Endosccopy, 108 Central Military Hospital, Hanoi, Vietnam. AD - Department of Medicine, Gastroenterology Section, Baylor College of Medicine and Michael E. DeBakey VA Medical Center, Texas, USA. AD - Department of Internal Medicine, Division of Gastroenterology, Jichi Medical University, Japan. AD - National Gastric Cancer and Gastrointestinal diseases Research Center, Pathumthani Thailand. Y1 - 2018 PY - 2018 VL - 19 IS - 12 SP - 3565 EP - 3569 KW - Helicobacter pylori KW - Gastritis KW - peptic ulcer disease KW - Gastric cancer KW - Southeast Asia DO - 10.31557/APJCP.2018.19.12.3565 N2 - Background: Helicobacter pylori (H. pylori) infection is currently considered as an infectious disease irrespective ofsymptoms and stage of disease. This study aimed to survey the impact of H. pylori infection and the current managementapproaches in Southeast Asian countries. Materials and methods: This is a survey among 26 experts from 9 SoutheastAsian countries (Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand and Vietnam),who attended a meeting to develop the ASEAN consensus on H. pylori management in November 2015. Results: Theprevalence of H. pylori varied significantly from 20% to 69% among countries, highest in Myanmar and lowest inMalaysia. The rate of H. pylori infection in patients with gastritis, peptic ulcer disease and gastric cancer (GC) alsovaried significantly, not only among countries but also among regions within the same country. The most commonmethod for H. pylori diagnosis before treatment was rapid urease test, followed by urea breath test. In multi-ethniccountries, some ethnic groups including Chinese, Batak and Minahasanese were considered as having higher risk ofGC. There have been no national screening programs for GC in all countries, and a majority of patients with GC werediagnosed in advanced stages with very poor 5-year survival. Conclusions: The prevalence of H. pylori infection andits infection rates in related gastrointestinal diseases were significantly different among Southeast Asian countries. Theprognosis of patients with GC in the region was very poor. The result of this survey is a platform for future internationaland regional research collaboration. UR - https://journal.waocp.org/article_80143.html L1 - https://journal.waocp.org/article_80143_9595c87bc0bd96f8afb13e60703b2e0d.pdf ER -