TY - JOUR ID - 88678 TI - Disparities in Epidemiological Profile of Gastric Adenocarcinoma in Selected Cities of Brazil JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 AU - Curado, Maria Paula AU - Silva, Diego Rodrigues Mendonça e AU - Oliveira, Max Moura de AU - Soares, Fernando AU - Begnami, Maria Dirlei AU - Coimbra, Felipe José Fernandez AU - Assumpção, Paulo Pimentel de AU - de Sant’Ana, Rosane Oliveira AU - Demachki, Samia AU - Dias-Neto, Emmanuel AD - Epidemiology and Statistics Nucleus, International Research Center, A.C.Camargo Cancer Center, Sao Paulo, Brazil. AD - Anatomic Pathology Department, Rede D'Or Hospitals, Sao Paulo, Brazil. AD - Department of Pathology, A.C.Camargo Cancer Center, Sao Paulo, Brazil. AD - Department of Abdominal Surgery, A.C.Camargo Cancer Center, Sao Paulo, Brazil. AD - Federal University of Pará, Brazil. AD - Hospital Haroldo Juaçaba, Cancer Institute of Ceará, Brazil. AD - Medical Genomics Laboratory, International Research Center, A.C.Camargo Cancer Center, Sao Paulo, Brazil. Y1 - 2019 PY - 2019 VL - 20 IS - 8 SP - 2253 EP - 2258 KW - Incidence KW - mortality KW - Trends KW - Gastric neoplasm KW - cohort effect DO - 10.31557/APJCP.2019.20.8.2253 N2 - Background: Despite decreasing global incidence trends, gastric cancer is still among the five most incident cancersin the world and the third cancer-related cause of death. In Brazil, differences in incidence and mortality exist dependingon the geographic region studied. Objective: To describe the incidence, mortality, trends and age-period-cohort ofgastric cancer in three cities of Brazil (Sao Paulo, Belem and Fortaleza), in the period 1990-2012. Mortality for gastriccancer in Brazil overall and by region was described. Methods: 33,462 incident cases of gastric cancer were identifiedfrom the population-based cancer registries and 23,424 deaths from mortality information system in residents ofthe three cities and in Brazil were included in the study. Data for incident cases were extracted from the PopulationBased Cancer Registries from the National Cancer Institute (INCA). Mortality data on gastric cancer were extractedfrom Information Technology Department of Brazilian Public Health Care System/Health Ministry (DATASUS/MS).Mortality and incidence age standardized rates were calculated. For trends analysis the Joinpoint Regression andage-period-cohort model were applied. Results: Belem presented the highest incidence rates for gastric adenocarcinoma.Decreasing incidence trends were identified in Sao Paulo (-7.8% in men; -6.3% in women) and in Fortaleza (-1.2%in men). Increasing incidence trends were observed for women in Belem (1.8%) and Fortaleza (1.1%). In Belem(Amazon area), there was an increased risk for gastric cancer in women born after the 1960s. Overall in Brazil mortalityfor gastric cancer is decreasing. Mortality trends showed significant reduction, for both sexes, in the three Braziliancities. Conclusion: Incidence of gastric cancer is increasing in women born in the sixties in Belem (Amazon region)and Fortaleza (Northeast region). In Brazil there was increase in mortality in Northeast region and decrease in othersregions. More update data on incidence for Amazon and Northeast region is needed. UR - https://journal.waocp.org/article_88678.html L1 - https://journal.waocp.org/article_88678_2682a6839b3cfc134c5427ce8ede1595.pdf ER -