TY - JOUR ID - 89060 TI - Association between Healthy Eating Index-2015 and Breast Cancer Risk: A Case-Control Study JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 AU - Kord- Varkaneh, Hamed AU - Salehi- Sahlabadi, Ammar AU - Zarezade, Meysam AU - Rahmani, Jamal AU - Tan, Shing Cheng AU - Hekmatdoost, Azita AU - Rashidkhani, Bahram AD - Student Research Committee, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. AD - Department of Clinical Nutrition, Student Research Committee, Nutrition Research Center, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran. AD - UKM Medical Molecular Biology Institute, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia. AD - Department of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Y1 - 2020 PY - 2020 VL - 21 IS - 5 SP - 1363 EP - 1367 KW - Healthy Eating Index-2015 KW - breast cancer KW - Diet DO - 10.31557/APJCP.2020.21.5.1363 N2 - Objective: Diet quality is known to influence cancer risk. The Healthy Eating Index (HEI) is one of the most frequently used measures of diet quality. However, the association between HEI-2015 and breast cancer risk is not known. The present study was undertaken to evaluate the association between HEI-2015 and breast cancer risk. Methods: A case-control study comprising 134 breast cancer patients and 265 cancer-free controls were conducted. Dietary intakes were assessed using a validated food frequency questionnaire (FFQ), from which the HEI-2015 score was calculated. Logistic regression was used to derive the odds ratios (ORs) for measuring the association between HEI-2015 scores and breast cancer risk. Results: Subjects in the top quartile of HEI-2015 had a 46% lower chance of breast cancer compared with subjects in the bottom quartile (OR 0.54; 95% CI 0.30, 0.98). After adjustment for potential confounders such as age, age at menarche, oral contraceptive drug use, menopausal status, marital status, body mass index, smoking and education level, the association between HEI-2015 score and a lower risk of breast cancer was enhanced (OR 0.32; 95% CI 0.16, 0.65). Conclusion: We successfully demonstrated that a higher HEI-2015 score was associated with a reduced breast cancer risk. UR - https://journal.waocp.org/article_89060.html L1 - https://journal.waocp.org/article_89060_f6583040281d985695f1541c27282505.pdf ER -