TY - JOUR ID - 89586 TI - Analysing the possibility of utilizing CBCT radiomics as an independent modality: a phantom study JO - Asian Pacific Journal of Cancer Prevention JA - APJCP LA - en SN - 1513-7368 AU - Palani, Dharmendran AU - Shanmugam, Senthilkumar AU - Govindaraj, Kesavan AD - Research and Development Centre, Bharathiar University, Coimbatore, India. AD - Department of Radiotherapy Government Rajaji Hospital & Madurai Medical College, Madurai, Tamil Nadu, India. AD - Research and Development Centre, Bharathiar University, Coimbatore, India. Y1 - 2021 PY - 2021 VL - 22 IS - 5 SP - 1383 EP - 1391 KW - Keywords: Texture KW - quantitative imaging features KW - Cone-beam CT KW - Computed Tomography DO - 10.31557/APJCP.2021.22.5.1383 N2 - Aim: To verify if computed tomography (CT) radiomics were reproducible by cone beam CT (CBCT) radiomics by using Catphan® 504. Materials and Methods: Catphan® 504 was imaged   using the default IGRT OBI  CBCT   imaging protocols and CT scanner. Seven known density image regions of the phantom were segmented and image feature was extracted by Imaging Biomarker Explorer (IBEX) software. The 49 selected features from four feature categories were analyzed by considering each region of interest (ROI) segment as individual image set. Correlation  was studies using interclass correlation coefficient (ICC) and Pearson’s correlation coefficient. Results: The ICC of the three feature categories, namely intensity, GLCM, and GLRLM was significant (p-value<0.05) in comparison with CT, while the ICC of the fourth feature category, NID, was no significant. The average absolute Pearson’s correlation coefficient from the features of the images was as follows: CT: r=0.679±0.257, CBCThead: r=0.707±0.231, CBCTthorax: r=0.643±0.260, and CBCTpelvis: r=0.594±0.276. Conclusion:  It seems that the various densities of Catphan® 504 ROI image segments of the CT radiomics are reproducible with CBCT radiomics and CBCT radiomics can be used as an independent modality. UR - https://journal.waocp.org/article_89586.html L1 - https://journal.waocp.org/article_89586_6e29fa69b7e2447d869dad37cb1f5f76.pdf ER -