It is becoming progressively more understandable that phytochemicals derived from edible plants haveshown potential in modelling their interactions with their target proteins. Rapidly accumulating in-vitroand in- vivo evidence indicates that anthocyanins have anticancer activity in rodent models of cancer. Moreintriguingly, evaluation of bilberry anthocyanins as chemopreventive agents in twenty-five colorectal cancerpatients has opened new window of opportunity in translating the findings from laboratory to clinic. Confluenceof information suggests that anthocyanins treated cancer cells reveal up-regulation of tumor suppressor genes.There is a successive increase in the research-work in nutrigenomics and evidence has started to shed lighton intracellular-signaling cascades as common molecular targets for anthocyanins. In this review we bring tol imelight how anthocyanins induced apoptosis in cancer cells via activation of extrinsic and intrinsic pathways.
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