Etiopathogenesis of Gastric Cancer

Document Type: Systematic Review and Meta-analysis

Authors

1 Department of Gastroenterology, Medical Faculty, Izmir University, Izmir, Turkey

2 Department of Gastroenterology, Medical Faculty, Izmir University, Izmir, Turkey *For correspondence: vegoral@hotmail.com

Abstract

Gastric cancer is a multifactorial and complex malignant disease seen commonly worldwide. It is one of the few malignant conditions in which the etiology involves infectious agents (Helicobacter pylori), but there are many other risk factors incuding high salt intake. Its pathogenesis generally involves interactions between environmental factors and genetic disposition. It is currently onsidered that stem cells may play a central role in gastric cancer development.

Keywords