Pattern and Time Trend of Stomach Cancers in Asia from 1950-99


Background: As there is a lack of data on stomach cancer disease in Asia, the aim of the present study was toexamine patterns and time trends for this neoplasm in Asian countries.
Methods: A descriptive study was designed to examine the cancer pattern and time trend and to calculate theannual change in mortality and incidence of stomach cancer at 5-year intervals. Data were derived from the WHOMortality Database, and Cancer Incidence in Five Continents.
Results: The highest rates of stomach cancer mortality and incidence (ASR) were observed in Japan, followed bythe Republic of Korea, and China, the lowest rates being observed in Thailand. The highest to lowest ratios were 50and 32 for mortality and 120 and 45 for incidence in males and females, respectively. A decreased trend of mortalitywas found in all 16 countries where mortality data was available, however, before the decrease, an increased trendwas found in Japan in the 1950s and in Sri-Lanka in the 1950-60s. In spite of a significant decrease in mortalitynationwide in Japan, an increased trend of stomach cancer incidence was found in Hiroshima (ASR + 7.4 in malesand + 1.5 in females for each 5-year period).Discussion: There are very large geographical differences in risk factors of stomach cancer from country tocountry, and these risk factors are still highly prevalent in specific areas of Asia. Further ecological study withemphasis on host and environmental factors for stomach cancer in Asian countries are strongly recommended.