Ultrasound Screening for Opisthorchis viverrini-associated Cholangiocarcinomas: Experience in an Endemic Area


In Thailand, liver cancer is the most common malignancy in males and the third most common among females. Inthe Northeast region, cholangiocarcinoma (CHCA) is the prevalent type, with Opisthorchis viverrini (OV), an endemicliver fluke, being considered the cause. We evaluated the role of ultrasound (U/S) for cholangiocarcinoma screeningas part of a larger cohort to characterize the linkage between liver fluke infestation and CHCA in Khon Kaen(Northeast Thailand). Most people (77%) had normal U/S findings while only 0.5% had suspected CHCA; thus, U/S should be used primarily for those with the highest risk, presenting symptoms and/or being OV positive.