Application of health informatics, especially for screening process of colorectal cancer, is a most effectiveand cost efficient method for monitoring, management and prevention of disease. Information systems havecapability for sharing and integration of information among the many stakeholders involved in colorectal cancercontrol (participant, family physician, specialist, hospitals, laboratories, and pharmacist). In this paper, weprovide comprehensive survey applications and functions of health informatics and information systems inpreventing colorectal cancer and management of screening process. Furthermore, we cover different models,infrastructures and standards for reporting and distribution of information at the international level, with dueattention to security and privacy issues. The information furnished in this article was collected from validmedical databases by medical librarians.