Overview of Chronic Myeloid Leukemia Patients in Pakistan in the Pre-Imatanib Era


Objectives: To study the patient characteristics of patients diagnosed with chronic myelogenous leukemia(CML) at a tertiary care cancer hospital in Pakistan. Methods and Materials: A retrospective analysis wasconducted on CML patients treated between 1996 and 2004 at Shaukat Khanum Memorial Cancer Hospital &Research Center.
Results: A total of 461 CML patient charts were reviewed. The mean and median ages atpresentation were much younger than in the prior reports in the western literature with a quicker progressionof disease.
Conclusion: The advent of tyrosine kinase inhibitors will likely have more impact on the lifespan ofCML patients in Pakistan when compared with patients in the western hemisphere due to younger age at diagnosis.