Aim: The present study was designed to evaluate effects of Plantago major extract on oxidative status in Wistaralbino rats administrated 7,12-dimethylbenz(a)anthracene (DMBA). Methods: Rats were divided into three equalgroups of 6 animals each: Group 1 controls, group 2 treated with DMBA (100 mg/kg, single dose) and group 3receiving the DMBA and the aqueous extract at 100 mg/kg/d for 60 days. Results: Significant decrease in catalase(P<0.05), carbonic anhydrase (p≤0.01), reduced glutathione (GSH) (P<0.01) and total protein (P<0.01) valueswas observed in the DMBA group compared with the healthy controls and DMBA + Plantago major groups. Conclusion: The results suggest preventive effects of Plantago major on DMBA induced oxidative damage inWistar albino rats that might be due to decreased free radical generation.
(2011). Plantago major Protective Effects on Antioxidant Status after Administration of 7,12-Dimethylbenz(a)anthracene in Rats. Asian Pacific Journal of Cancer Prevention, 12(2), 531-535.
MLA
. "Plantago major Protective Effects on Antioxidant Status after Administration of 7,12-Dimethylbenz(a)anthracene in Rats". Asian Pacific Journal of Cancer Prevention, 12, 2, 2011, 531-535.
HARVARD
(2011). 'Plantago major Protective Effects on Antioxidant Status after Administration of 7,12-Dimethylbenz(a)anthracene in Rats', Asian Pacific Journal of Cancer Prevention, 12(2), pp. 531-535.
VANCOUVER
Plantago major Protective Effects on Antioxidant Status after Administration of 7,12-Dimethylbenz(a)anthracene in Rats. Asian Pacific Journal of Cancer Prevention, 2011; 12(2): 531-535.
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