This was a survey research conducted in Northestern Thailand during 2009-2010 and designed to evaluatethe success of a health education program by comparing levels of health knowledge in the community before andafter the launching of a Multi-professional Intervention and Training for Ongoing Volunteer-based CommunityHealth Programme. The survey questionnaire included items about demographic characteristics and healthknowledge. The participants were 1,015 members of various communities, who were randomly selected to beincluded in the survey before launching the intervention, and 1,030 members of the same communities randomlyselected to be included in the survey after the intervention was completed. The demographic characteristics ofboth groups were similar. Overall knowledge and knowledge of all the diseases, except lung and cervical cancer,were significantly higher after the intervention. In conclusion, a Volunteer-based Community Health Programmehas advantages for areas where the numbers of health personnel are limited. The use of trained communityhealth volunteers may be one of the best sustainable alternative means for the transfer of health knowledge.