Estimating the Five-Year Survival of Cervical Cancer PatientsTreated in Hospital Universiti Sains Malaysia


Objective: The objective of this study was to determine the five-year survival among patients with cervicalcancer treated in Hospital Universiti Sains Malaysia.
Methods: One hundred and twenty cervical cancer patientsdiagnosed between 1st July 1995 and 30th June 2007 were identified. Data were obtained from medical records.The survival probability was determined using the Kaplan-Meier method and the log-rank test was applied tocompare the survival distribution between groups.
Results: The overall five-year survival was 39.7% [95%CI(Confidence Interval): 30.7, 51.3] with a median survival time of 40.8 (95%CI: 34.0, 62.0) months. The log-ranktest showed that there were survival differences between the groups for the following variables: stage at diagnosis(p=0.005); and primary treatment (p=0.0242). Patients who were diagnosed at the latest stage (III-IV) were foundto have the lowest survival, 18.4% (95%CI: 6.75, 50.1), compared to stage I and II where the five-year survivalwas 54.7% (95%CI: 38.7, 77.2) and 40.8% (95%CI: 27.7, 60.3), respectively. The five-year survival was higher inpatients who received surgery [52.6% (95%CI: 37.5, 73.6)] as a primary treatment compared to the non-surgicalgroup [33.3% (95%CI: 22.9, 48.4)].
Conclusion: The five-year survival of cervical cancer patients in this studywas low. The survival of those diagnosed at an advanced stage was low compared to early stages. In addition,those who underwent surgery had higher survival than those who had no surgery for primary treatment.