Recent investigations have confirmed up-regulation of serum miR-21 and its diagnostic and prognostic valuein several human malignancies. In this study, we examined serum miR-21 levels in epithelial ovarian cancer(EOC) patients, and explored its association with clinicopathological factors and prognosis. The results showedsignificantly higher serum miR-21 levels in EOC patients than in healthy controls. In addition, increased serummiR-21 expression was correlated with advanced FIGO stage, high tumor grade, and shortened overall survival.These findings indicate that serum miR-21 may serve as a novel diagnostic and prognostic marker, and be usedas a therapeutic target for the treatment of EOC.
(2013). Identification of Serum MicroRNA-21 as a Biomarker for EarlyDetection and Prognosis in Human Epithelial Ovarian Cancer. Asian Pacific Journal of Cancer Prevention, 14(2), 1057-1060.
MLA
. "Identification of Serum MicroRNA-21 as a Biomarker for EarlyDetection and Prognosis in Human Epithelial Ovarian Cancer". Asian Pacific Journal of Cancer Prevention, 14, 2, 2013, 1057-1060.
HARVARD
(2013). 'Identification of Serum MicroRNA-21 as a Biomarker for EarlyDetection and Prognosis in Human Epithelial Ovarian Cancer', Asian Pacific Journal of Cancer Prevention, 14(2), pp. 1057-1060.
VANCOUVER
Identification of Serum MicroRNA-21 as a Biomarker for EarlyDetection and Prognosis in Human Epithelial Ovarian Cancer. Asian Pacific Journal of Cancer Prevention, 2013; 14(2): 1057-1060.
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