Several lines of evidence indicate that cancer is a multistep process. To survey the mechanisms involving genealteration and miRNAs in adrenocortical cancer, we focused on transcriptional factors as a point of penetrationto build a regulatory network. We derived three level networks: differentially expressed; related; and global. Atopology network ws then set up for development of adrenocortical cancer. In this network, we found that somepathways with differentially expressed elements (genetic and miRNA) showed some self-adaption relations, suchas EGFR. The differentially expressed elements partially uncovered mechanistic changes for adrenocorticalcancer which should guide medical researchers to further achieve pertinent research.
(2013). Complex Regulatory Network of MicroRNAs, Transcription Factors, Gene Alterations in Adrenocortical Cancer. Asian Pacific Journal of Cancer Prevention, 14(4), 2265-2268.
MLA
. "Complex Regulatory Network of MicroRNAs, Transcription Factors, Gene Alterations in Adrenocortical Cancer". Asian Pacific Journal of Cancer Prevention, 14, 4, 2013, 2265-2268.
HARVARD
(2013). 'Complex Regulatory Network of MicroRNAs, Transcription Factors, Gene Alterations in Adrenocortical Cancer', Asian Pacific Journal of Cancer Prevention, 14(4), pp. 2265-2268.
VANCOUVER
Complex Regulatory Network of MicroRNAs, Transcription Factors, Gene Alterations in Adrenocortical Cancer. Asian Pacific Journal of Cancer Prevention, 2013; 14(4): 2265-2268.
)