miR-421, miR-155 and miR-650: Emerging Trends of Regulation of Cancer and Apoptosis


It is becoming progressively more understandable that between transcription and translation there liesanother versatile regulator that quantitatively controls the expression of mRNAs. Identification of miRNAs askey regulators of wide ranging signaling cascades and modulators of different cell-type and context dependentactivities attracted basic and clinical scientists to study modes and mechanisms in details. In line with thisapproach overwhelmingly increasing in vivo and in vitro studies are deepening our understanding regardingmiR-421, mir-155 and miR-650 mediated regulation of cellular activities. We also attempt to provide an overviewof long non coding RNAs.